Highlights publications 2018

Amin N, Vrij FM de, Baghdadi M, Brouwer RW, Rooij JG van, Jovanova O, Uitterlinden AG, Hofman A, Janssen HL, Murad SD, Kraaij R, Stedehouder J, Hout MC van den, Kros JM, IJcken WF van, Tiemeier H, Kushner SA, Duijn CM van. A rare missense variant in RCL1 segregates with depression in extended families. Mol Psychiatry 2018; 23(5): 1120-1126.

Amin N, Vrij FM de, Baghdadi M, Brouwer RW, Rooij JG van, Jovanova O, Uitterlinden AG, Hofman A, Janssen HL, Murad SD, Kraaij R, Stedehouder J, Hout MC van den, Kros JM, IJcken WF van, Tiemeier H, Kushner SA, Duijn CM van. Employed family-based genetic discovery combining linkage analysis and exome sequencing to identify RCL 1 as a novel candidate gene for depression, with independent replication in a population-based cohort. Mol Psychiatry 2018; 23(5): 1093.

Bergink V, Pop VJM, Nielsen PR, Agerbo E, Munk-Olsen T, Liu X. Comorbidity of autoimmune thyroid disorders and psychiatric disorders during the postpartum period: a Danish nationwide register-based cohort study. Psychol Med 2018; 48(8): 1291-1298.

Bowling AB, Tiemeier HW, Jaddoe VWV, Barker ED, Jansen PW. ADHA symptoms and body composition changes in childhood: a longitudinal study evaluating directionality of associations. Pediatr Obes 2018; 13(9): 567-575.

Brouwer ME, Williams AD, Grinsven SE van Cuijpers P, Lambregtse-van den Berg MP, Burger H, Bockting CLH. Offspring outcomes after prenatal interventions for common mental disorders: a meta-analysis. BMC Med 2018; 16(1): 208.

Diermen L van, Ameele S van den, Kamperman AM, Sabbe BCG, Vermeulen T, Schrijvers D, Birkenhager TK. Prediction of electroconvulsive therapy response and remission in major depression: a meta-analysis. Br J Psychiatry 2018; 212(2): 71-80.

Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L, Dwyer T, Eng C, Eskenazi B, Everson TM, Falahi F, Fallin MD, Farchi S, Fernandez MF, Gao L, Gaunt TR, Ghantous A, Gillman MW, Gonseth S, Grote V, Gruzieva O, Håberg SE, Herceg Z, Hivert MF, Holland N, Holloway JW, Hoyo C, Hu D, Huang RC, Huen K, Järvelin MR, Jima DD, Just AC, Karagas MR, Karlsson R, Karmaus W, Kechris KJ, Kere J, Kogevinas M, Koletzko B, Koppelman GH, Küpers LK, Ladd-Acosta C, Lahti J, Lambrechts N, Langie SAS, Lie RT, Liu AH, Magnus MC, Magnus P, Maguire RL, Marsit CJ, McArdle W, Melén E, Melton P, Murphy SK, Nawrot TS, Nisticò L, Nohr EA, Nordlund B, Nystad W, Oh SS, Oken E, Page CM, Perron P, Pershagen G, Pizzi C, Plusquin M, Raikkonen K, Reese SE, Reischl E, Richiardi L, Ring S, Roy RP, Rzehak P, Schoeters G, Schwartz DA, Sebert S, Snieder H, Sørensen TIA, Starling AP, Sunyer J, Taylor JA, Tiemeier H, Ullemar V, Vafeiadi M, Van Ijzendoorn MH, Vonk JM, Vriens A, Vrijheid M, Wang P, Wiemels JL, Wilcox AJ, Wright RJ, Xu CJ, Xu Z, Yang IV, Yousefi P, Zhang H, Zhang W, Zhao S, Agha G, Relton CL, Jaddoe VWV, London SJ. Cohort profile: pregnancy and childhood epigenetics (PACE) consortium. Int J Epidemiol 2018; 47(1): 22-23.

Freak-Poli R, Ikram MA, Franco OH, Hofman A, Tiemeier H. Depressive symptoms prior to and after incident cardiovascular disease and long-term survival. A population-based study of older persons. Depress Anxiety 2018; 35(1): 18-31.

Galbally M, Bergink V, Vigod SN, Buist A, Boyce P, Chandra P, Kohan R, Howard LM. Breastfeeding and lithium: is breast always best? Lancet Psychiatry 2018; 5(7): 534-536.

Grootendorst-van Mil NH, Tiemeier H, Steenweg-de Graaff J, Koletzko B, Demmelmair H, Jaddoe VWV, Steegers EAP, Steegers-Theunissen RPM. Maternal plasma n-3 and n-6 polyunsaturated fatty acids during pregnancy and features of fetal health: fetal growth velocity, birth weight and duration of pregnancy. Clin Nutr 2018; 37(4): 1367-1374.

Gunhanlar N, Shpak G, Kroeg M van der, Gouty-Colomer LA, Munshi ST, Lendemeijer B, Ghazvini M, Dupont C, Hoogendijk WJG, Gribnau J, Vrij FMS de, Kushner SA. A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells. Mol Psychiatry 2018; 23(5): 1336-1344.

Jansen PR, Polderman TJC, Bolhuis K, Ende J van der, Jaddoe VWV, Verhulst FC, White T, Posthuma D, Tiemeier H. Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population. J Child Psychol Psychiatry 2018; 59(1): 39-47.

Koolhaas CM, Dhana K, Schoufour JD, Lahousse L, Rooij FJA van, Ikram MA, Brusselle G, Tiemeier H, Franco OH. Physical activity and cause-specific mortality: the Rotterdam Study. Int J Epidemiol 2018; 47(5): 1705-1713.

Laurenssen EMP, Leyten P, Kikkert MJ, Westra D, Peen J, Soons MBJ, Dam AM van, Broekhuyzen AJ van, Blankers M, Busschbach JJV, Dekker JJM. Day hospital mentalization-based treatment v. specialist treatment as usual in patients with borderline personality disorder: randomized controlled trial. Psychol Med 2018; 48(15): 2522-2529.

Linscott RJ, Morton SE, GROUP investigators (including Beveren N van). The latent taxonicity of schizotypy in biological siblings of probands with schizophrenia. Schizophr Bull 2018; 44(4): 922-932.

Marroun H El, Zou R, Muetzel RL, Jaddoe VW, Verhulst FC, White T, Tiemeier H. Prenatal exposure to maternal and paternal depressive symptoms and white matter microstructure in children. Depress Anxiety 2018; 35: 321-329.

Mirza SS, Ikram MA, Freak-Poli R, Hofman A, Rizopoulos D, Tiemeier H. 12-year trajectories of depressive symptoms in community-dwelling older adults and the subsequent risk of death of 13 years. J Gerontol A Biol Sci Med Sci 2018; 73(6): 820-827.

Munk-Olsen T, Liu X, Viktorin A, Brown HK, Di Florio A, D’Onofrio BM, Gomes T, Howard LM, Khalifeh H, Krohn H, Larsson H, Lichtenstein P, Taylor CL, Kamp I van, Wesseloo R, Meltzer-Brody S, Vigod SN, Bergink V. Maternal and infant outcomes associated with lithium use in pregnancy: an international collaborative meta-analysis of six cohort studies. Lancet Psychiatry 2018; 5(8): 644-652.

Mutlu U, Colijn JM, Ikram MA, Bonnemaijer PWM, Licher S, Wolters FJ, Tiemeier H, Koudstaal PJ, Klaver CCW, Ikram MK. Association of retinal neurodegeneration on optical coherence tomography with dementia: a population-based study. JAMA Neurol 2018; 75(10): 1256-1263.

Purba FD, Hunfeld JAM, Timman R, Iskandarsyah A, Fitriana TS, Sadarjoen SS, Passchier J, Busschbach JJ. Test-retest reliability of EQ-5D-5L valuation techniques: the composite time trade-off and discrete choice experiments. Value Health 2018; 21(10): 1243-1249.

Schmitz N, Deschenes SS, Burns RJ, Danna SM, Franco OH, Ikram MA, Kivimaki M, Singh-Manoux A, Tiemeier H. Cardiometabolic dysregulation and cognitive decline: potential role of depressive symptoms. Br J Psychiatry 2018; 212(2): 96-102.

Serdarevic F, Jansen PR, Ghassabian A, White T, Jaddoe VWV, Posthuma D, Tiemeier H. Association of genetic risk for schizophrenia and bipolar disorder with infant neuromotor development. JAMA Psychiatry 2018; 75(1): 96-98.

Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, Bülow R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Valdés Hernández MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M. Genome-wide association study of 23,500 individuals indentifies 7 loci associated with brain ventricular volume. Nat Commun 2018; 9(1): 3945.

Wierdsma AI, Mulder CL. Cost sharing does not lead to an overall increase of involuntary commitments in the Netherlands. JAMA Psychiatry 2018; 75(2): 213.

Wong ELY, Shah K, Cheung AWL, Wong AYK, Visser M, Stolk E. Evaluation of Split Version and Feedback Module on the Improvement of Time Trade-Off Data. Value in Health 2018; 21 (6), 732-741.

Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke TK, Coleman JIR, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, Kiadeh FHF, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, Hickie IB, Hoffmann P, Homuth G, Horn C, Hottenga JJ, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi Y, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O'Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pedersen CB, Pedersen MG, Peterson RE, Pettersson E, Peyrot WJ, Pistis G, Posthuma D, Purcell SM, Quiroz JA, Qvist P, Rice JP, Riley BP, Rivera M, Saeed Mirza S, Saxena R, Schoevers R, Schulte EC, Shen L, Shi J, Shyn SI, Sigurdsson E, Sinnamon GBC, Smit JH, Smith DJ, Stefansson H, Steinberg S, Stockmeier CA, Streit F, Strohmaier J, Tansey KE, Teismann H, Teumer A, Thompson W, Thomson PA, Thorgeirsson TE, Tian C, Traylor M, Treutlein J, Trubetskoy V, Uitterlinden AG, Umbricht D, Van der Auwera S, van Hemert AM, Viktorin A, Visscher PM, Wang Y, Webb BT, Weinsheimer SM, Wellmann J, Willemsen G, Witt SH, Wu Y, Xi HS, Yang J, Zhang F; eQTLGen; 23andMe, Arolt V, Baune BT, Berger K, Boomsma DI, Cichon S, Dannlowski U, de Geus ECJ, DePaulo JR, Domenici E, Domschke K, Esko T, Grabe HJ, Hamilton SP, Hayward C, Heath AC, Hinds DA, Kendler KS, Kloiber S, Lewis G, Li QS, Lucae S, Madden PFA, Magnusson PK, Martin NG, McIntosh AM, Metspalu A, Mors O, Mortensen PB, Müller-Myhsok B, Nordentoft M, Nöthen MM, O'Donovan MC, Paciga SA, Pedersen NL, Penninx BWJH, Perlis RH, Porteous DJ, Potash JB, Preisig M, Rietschel M, Schaefer C, Schulze TG, Smoller JW, Stefansson K, Tiemeier H, Uher R, Völzke H, Weissman MM, Werge T, Winslow AR, Lewis CM, Levinson DF, Breen G, Børglum AD, Sullivan PF; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nat Genet 2018; 50(5): 668-681.

Wusten C, Schlier B, Jaya ES, Genetic Risk and Outcome of Psychosis (GROUP) Investigators (including van Beveren NJ), Fonseca-Pedrero E, Peters E, Verdoux H, Woodward TS, Ziermans TB, Lincoln TM. Psychotic experience and related distress: a cross-national comparison and network analysis based on 7141 participants from 13 countries. Schizophr Bull 2018; 44(6): 1185-1194.

Yang Z, Luo N, Bonsel GJ, Busschbach JJ van, Stolk E. Selecting Health States for EQ-5D-3L Valuation Studies: Statistical Considerations Matter. Value in Health 2018; 21(4), 456-461.

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Highlights publications 2017

Amin N, Jovanova O, Adams HH, Dehghan A, Kavoushi M, Vernooij MW, Peeters RP, Vrij FM de, Lee SJ van der, Rooij JG van, Leeuwen EM van, Chaker L, Demirkan A, Brouwer RW, Kraaij R, Willems van Dijk K, Hankemeier T, IJcken WF van, Uitterlinden AG, Niessen WJ, Franco OH, Kushner SA, Ikram MA, Tiemeier H, Duijn CM van. Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms. Mol Psychiatry 2017; 22(4): 537-543.

Bolhuis K, Lubke GH, Ende J van der, Bartels M, Beijsterveldt CEM van, Lichtenstein P, Larsson H, Jaddoe VWV, Kushner SA, Verhulst FC, Boomsma DI, Tiemeier H. Disentangling heterogeneity of childhood disruptive behavior problems into dimensions and subgroups. J Am Acad Child Adolesc Psychiatry 2017; 56(8): 678-686.

Bouwkamp CG, Kievit AJA, Markx S, Friedman JI, Zutven L van, Minkelen R van, Vrijenhoek T, Xu B, Sterrenburg-van de Nieuwegiessen I, Veltman JA, Bonifati V, Kushner SA. Copy number variation in syndromic forms of psychiatric illness: the emerging value of clinical genetic testing in psychiatry. Am J Psychiatry 2017; 174: 1036-1050.

Burgerhout KM, Kamperman AM, Roza SJ, Lambregtse-Van den Berg MP, Koorengevel KM, Hoogendijk WJ, Kushner SA, Bergink V. Functional recovery after postpartum psychosis: a prospective longitudinal study. J Clin Psychiatry 2017; 78(1): 122-128.

Derks IP, Tiemeier H, Sijbrands EJ, Nicholson JM, Voortman T, Verhulst FC, Jaddoe VW, Jansen PW. Testing the direction of effects between child body composition and restrictive feeding practices: results from a population-based cohort. Am J Clin Nutri 2017; 106(3): 783-790.

Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DH, Boomsma D, Breen G, Buttenschøn HN, Byrne EM, Børglum AD, Castelao E, Cichon S, Clarke TK, Cornelis MC, Dannlowski U, De Jager PL, Demirkan A, Domenici E, van Duijn CM, Dunn EC, Eriksson JG, Esko T, Faul JD, Ferrucci L, Fornage M, de Geus E, Gill M, Gordon SD, Grabe HJ, van Grootheest G, Hamilton SP, Hartman CA, Heath AC, Hek K, Hofman A, Homuth G, Horn C, Jan Hottenga J, Kardia SL, Kloiber S, Koenen K, Kutalik Z, Ladwig KH, Lahti J, Levinson DF, Lewis CM, Lewis G, Li QS, Llewellyn DJ, Lucae S, Lunetta KL, MacIntyre DJ, Madden P, Martin NG, McIntosh AM, Metspalu A, Milaneschi Y, Montgomery GW, Mors O, Mosley TH Jr, Murabito JM, Müller-Myhsok B, Nöthen MM, Nyholt DR, O'Donovan MC, Penninx BW, Pergadia ML, Perlis R, Potash JB, Preisig M, Purcell SM, Quiroz JA, Räikkönen K, Rice JP, Rietschel M, Rivera M, Schulze TG, Shi J, Shyn S, Sinnamon GC, Smit JH, Smoller JW, Snieder H, Tanaka T, Tansey KE, Teumer A, Uher R, Umbricht D, Van der Auwera S, Ware EB, Weir DR, Weissman MM, Willemsen G, Yang J, Zhao W, Tiemeier H, Sullivan PF. An analysis of two genome-wide association meta-analyses identifies a new locus for broad depression phenotype. Biol Psychiatry 2017; 82(5): 322-329.

Esbroeck ACM van, Janssen APA, Cognetta AB 3rd, Ogasawara D, Shpak G, van der Kroeg M, Kantae V, Baggelaar MP, de Vrij FMS, Deng H, Allarà M, Fezza F, Lin Z, van der Wel T, Soethoudt M, Mock ED, den Dulk H, Baak IL, Florea BI, Hendriks G, De Petrocellis L, Overkleeft HS, Hankemeier T, De Zeeuw CI, Di Marzo V, Maccarrone M, Cravatt BF, Kushner SA, van der Stelt M. Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474. Science 2017; 356(6342): 1084-1087.

Florio A Di, Munk-Olsen T, Bergink V. Lithium use in pregnancy and the risk of cardiac malformations. N Engl J Med 2017; 377(9): 893.

Florio A Di, Putnam K, Altemus M, Apter G, Bergink V, Bilszta J, Brock R, Buist A, Deligiannidis DM, Devouche E, Epperson CN, Guille C, Kom D, Lichtenstein P, Magnusson PK, Martinez P, Munk-Olsen T, Newport J, Payne J, Penninx BW, O’Hara M, Robertson-Blackmore E, Roza SJ, Sharkey KM, Stuart S, Tiemeier H, Viktorin A, Schmidt PJ, Sullivan PF, Stowe ZN, Wisner KL, Jones I, Rubinow DR, Meltzer-Brody S. The impact of education, country, race and ethnicity on the self-report of postpartum depression using the Edinburgh Postnatal Depression Scale. Psychol Med 2017; 47(5): 787-799.

Garcia AH, Erler NS, Jaddoe VW, Tiemeier H, Hooven EH van den, Franco OH, Rivadeneira F, Voortman T. 25-hydroxyvitamin D concentrations during fetal life and bone health in children aged 6 years: a population-based prospective cohort study. Lancet Diabetes Endocrinol 2017; 5(5): 367-376.

Howes OD, McCutcheon R, Agid O, de Bartolomeis A, van Beveren NJ, Birnbaum ML, Bloomfield MA, Bressan RA, Buchanan RW, Carpenter WT, Castle DJ, Citrome L, Daskalakis ZJ, Davidson M, Drake RJ, Dursun S, Ebdrup BH, Elkis H, Falkai P, Fleischacker WW, Gadelha A, Gaughran F, Glenthøj BY, Graff-Guerrero A, Hallak JE, Honer WG, Kennedy J, Kinon BJ, Lawrie SM, Lee J, Leweke FM, MacCabe JH, McNabb CB, Meltzer H, Möller HJ, Nakajima S, Pantelis C, Reis Marques T, Remington G, Rossell SL, Russell BR, Siu CO, Suzuki T, Sommer IE, Taylor D, Thomas N, Üçok A, Umbricht D, Walters JT, Kane J, Correll CU. Treatment-resistant schizophrenia: treatment response and resistance in psychosis (TRRIP) working group consensus guidelines on diagnosis and terminology. Am J Psychiatry 2017; 174(3): 216-229.

Ikram MA, Brusselle GGO, Murad SD, Duijn CM van, Franco OH, Goedegebure A, Klaver CCW, Nijsten TEC, Peeters RP, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Hofman A. The Rotterdam Study: 2018 update on objectives, design and main results. Eur J Epidemiol 2017; 32(9): 807-850.

Jairam AP, Timmermans L, Eker HH, Pierik REGJM, Klaveren D van, Steyerberg EW, Timman R, Ham AC van der, Dawson I, Charbon JA, Schuhmacher C, Mihaljevic A, Izbicki JR, Fikatas P, Knebel P, Fortelny RH, Kleinrensink GJ, Lange JF, Jeekel HJ, PRIMA Trialist Group. Prevention if incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial. Lancet 2017; 390(10094): 567-576.

Jaspers L, Schoufour JD, Erler NS, Darweesh SK, Portegies ML, Sedaqhat S, Lahousse L, Brusselle GG, Stricker BH, Tiemeier H, Ikram MA, Laven JS, Franco OH, Kavousi M. Development of a healthy aging score in de population-based Rotterdam Study: evaluating age and sex differences. J Am Med Dir Assoc 2017; 18(3): 276.e1-276.e7.

Jong JH de, Vigueras-Guillen JP, Simon TC, Timman R, Peto T, Vermeer KA, Meurs JC van. Preoperative posturing of patients with Macuala-on retinal detachment reduces progression toward the fovea. Ophthalmology 2017; 124(10): 1510-1522.

Jovanova O, Aarts N, Noordam R, Carola-Zillikens M, Hofman A, Tiemeier H. Vitamin D serum levels are cross-sectionally but not prospectively associated with late-life depression. Acta Psychiatr Scand 2017; 135(3): 185-194.

Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, Perez J, Eicher JD, Kutalik Z, Xue L, Mahajan A, Renström F, Wu J, Qi Q, Ahmad S, Alfred T, Amin N, Bielak LF, Bonnefond A, Bragg J, Cadby G, Chittani M, Coggeshall S, Corre T, Direk N, Eriksson J, Fischer K, Gorski M, Neergaard Harder M, Horikoshi M, Huang T, Huffman JE, Jackson AU, Justesen JM, Kanoni S, Kinnunen L, Kleber ME, Komulainen P, Kumari M, Lim U, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Marten J, Middelberg RPS, Müller-Nurasyid M, Navarro P, Pérusse L, Pervjakova N, Sarti C, Smith AV, Smith JA, Stančáková A, Strawbridge RJ, Stringham HM, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van der Most PJ, Van Vliet-Ostaptchouk JV, Vedantam SL, Verweij N, Vink JM, Vitart V, Wu Y, Yengo L, Zhang W, Hua Zhao J, Zimmermann ME, Zubair N, Abecasis GR, Adair LS, Afaq S, Afzal U, Bakker SJL, Bartz TM, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Braga D, Buckley BM, Buyske S, Campbell H, Chambers JC, Collins FS, Curran JE, de Borst GJ, de Craen AJM, de Geus EJC, Dedoussis G, Delgado GE, den Ruijter HM, Eiriksdottir G, Eriksson AL, Esko T, Faul JD, Ford I, Forrester T, Gertow K, Gigante B, Glorioso N, Gong J, Grallert H, Grammer TB, Grarup N, Haitjema S, Hallmans G, Hamsten A, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie ND, Heath AC, Hernandez D, Hindorff L, Hocking LJ, Hollensted M, Holmen OL, Homuth G, Jan Hottenga J, Huang J, Hung J, Hutri-Kähönen N, Ingelsson E, James AL, Jansson JO, Jarvelin MR, Jhun MA, Jørgensen ME, Juonala M, Kähönen M, Karlsson M, Koistinen HA, Kolcic I, Kolovou G, Kooperberg C, Krämer BK, Kuusisto J, Kvaløy K, Lakka TA, Langenberg C, Launer LJ, Leander K, Lee NR, Lind L, Lindgren CM, Linneberg A, Lobbens S, Loh M, Lorentzon M, Luben R, Lubke G, Ludolph-Donislawski A, Lupoli S, Madden PAF, Männikkö R, Marques-Vidal P, Martin NG, McKenzie CA, McKnight B, Mellström D, Menni C, Montgomery GW, Musk AB, Narisu N, Nauck M, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Peyser PA, Pisinger C, Porteous DJ, Raitakari OT, Rankinen T, Rao DC, Rasmussen-Torvik LJ, Rawal R, Rice T, Ridker PM, Rose LM, Bien SA, Rudan I, Sanna S, Sarzynski MA, Sattar N, Savonen K, Schlessinger D, Scholtens S, Schurmann C, Scott RA, Sennblad B, Siemelink MA, Silbernagel G, Slagboom PE, Snieder H, Staessen JA, Stott DJ, Swertz MA, Swift AJ, Taylor KD, Tayo BO, Thorand B, Thuillier D, Tuomilehto J, Uitterlinden AG, Vandenput L, Vohl MC, Völzke H, Vonk JM, Waeber G, Waldenberger M, Westendorp RGJ, Wild S, Willemsen G, Wolffenbuttel BHR, Wong A, Wright AF, Zhao W, Zillikens MC, Baldassarre D, Balkau B, Bandinelli S, Böger CA, Boomsma DI, Bouchard C, Bruinenberg M, Chasman DI, Chen YD, Chines PS, Cooper RS, Cucca F, Cusi D, Faire U, Ferrucci L, Franks PW, Froguel P, Gordon-Larsen P, Grabe HJ, Gudnason V, Haiman CA, Hayward C, Hveem K, Johnson AD, Wouter Jukema J, Kardia SLR, Kivimaki M, Kooner JS, Kuh D, Laakso M, Lehtimäki T, Marchand LL, März W, McCarthy MI, Metspalu A, Morris AP, Ohlsson C, Palmer LJ, Pasterkamp G, Pedersen O, Peters A, Peters U, Polasek O, Psaty BM, Qi L, Rauramaa R, Smith BH, Sørensen TIA, Strauch K, Tiemeier H, Tremoli E, van der Harst P, Vestergaard H, Vollenweider P, Wareham NJ, Weir DR, Whitfield JB, Wilson JF, Tyrrell J, Frayling TM, Barroso I, Boehnke M, Deloukas P, Fox CS, Hirschhorn JN, Hunter DJ, Spector TD, Strachan DP, van Duijn CM, Heid IM, Mohlke KL, Marchini J, Loos RJF, Kilpeläinen TO, Liu CT, Borecki IB, North KE, Cupples LA. Genome-wide meta-analysis of 241,258 adults accounting for smoking behavior identifies novel loci for obesity traits. Nat Commun 2017;8:14977.

Levitan RD, Jansen P, Wendland B, Tiemeier H, Jaddoe VW, Silveira PP, Kennedy JL, Atkinson L, Fleming A, Sokolowski M, Gaudreau H, Steiner M, Dube L, Hamilton J, Moss E, Wazana A, Meaney M. A DRD4 gene by maternal sensitivity interaction predicts risk for overweight or obesity in tow independent cohorts of preschool children. J Child Psychol Psychiatry 2017; 58(2): 180-188.

Liu X, Agerbo E, Ingstrup KG, Musliner K, Meltzer-Brody S, Bergink V, Munk-Olsen T. Antidepressant use during pregnancy and psychiatric disorders in offspring: Danish nationwide register based cohort study. BMJ 2017; 358: j3668.

Liu X, Agerbo E, Li J, Meltzer-Brody S, Bergink V, Munk-Olsen T. Depression and anxiety in the postpartum period and risk of bipolar disorder: a Danish nationwide register-based cohort study. J Clin Psychiatry 2017; 78(5): e469-e476.

Lubczyńska MJ, Sunyer J, Tiemeier H, Porta D, Kasper-Sonnenberg M, Jaddoe VWV, Basagaña X, Dalmau-Bueno A, Forastiere F, Wittsiepe J, Hoffmann B, Nieuwenhuijsen M, Hoek G, de Hoogh K, Brunekreef B, Guxens M. Exposure of self-esteem on perceived orthodontic treatment need and oral health-related quality of life in children: the Generation R Study. Environ Int 2017; 109: 170-180.

Lukoshe A, Bosch GE van den, Lugt A van der, Kushner SA, Hokken-Koelega AC, White T. Aberrant white matter microstructure in children and adolescents with the subtype of Prader-Willi syndrome at high risk for psychosis. Schizophr Bull 2017; 43(5): 1090-1099.

Mamede Studart Soares S, Gog TAJM van, Klein Nagelvoort - Schuit SCE, Berge K van den, Daele PLA van, Bueving HJ, Zee T van der, Broek WW van den, Saase JLCM van, Schmidt HG . Why patients' disruptive behaviours impair diagnostic reasoning: a randomised experiment. BMJ Quality & Safety 2017; 26 (1): 13-18.

Manen MJG van, Spijker A van ‘t, Tak NC, Baars CT, Jongenotter SM, Roon LR van, Kraan J, Hoogsteden HC, Wijsenbeek MS. Patient and partner empowerment programme for idiopathic pulmonary fibrosis. Eur Respir J 2017; 49(4): 1601596.

Mirza SS, Ikram MA, Bos D, Mihaescu R, Hofman A, Tiemeier H. Mild cognitive impairment and risk of depression and anxiety: a population-based study. Alzheimers Dement 2017; 13(2): 130-139.

Noordraven EL, Wierdsma AI, Blanken P, Bloemendaal AF, Staring AB, Mulder CL. Financial incentives for improving adherence to maintenance treatment in patients with psychotic disorders (Money for Medication): a multicentre, open-label, randomised controlled trial. Lancet Psychiatry 2017; 4(3): 199-207.

Putnam KT, Wilcox M, Robertson-Blackmore E, Sharkey K, Bergink V, Munk-Olsen T, Deligiannidis KM, Payne J, Altemus M, Newport J, Apter G, Devouche E, Viktorin A, Magnusson P, Penninx B, Buist A, Bilszta J, O'Hara M, Stuart S, Brock R, Roza S, Tiemeier H, Guille C, Epperson CN, Kim D, Schmidt P, Martinez P, Di Florio A, Wisner KL, Stowe Z, Jones I, Sullivan PF, Rubinow D, Wildenhaus K, Meltzer-Brody S; Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium. Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium. Lancet Psychiatry 2017; 4(6): 477-485.

Ramos-Goni JM, Oppe M, Slaap B, Busschbach JJ, Stolk E. Quality control process for EQ-5D-5L validation studies. Value Health 2017; 20(3): 466-473.

Riga D, Kramvis I, Koskinen MK, Bokhoven P van, Harst JE van der, Heistek TS, Timmerman JA, Nierop P van, Schors RC van der, Pieneman AW, Weger A de, Mourik Y van, Schoffelmeer ANM, Mansvelder HD, Meredith RM, Hoogendijk WJG, Smit AB, Spijker S. Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats. Sci Transl Med 2017; 9(421).

Sajjad A, Freak-Poli RL, Hofman a, Roza SJ, Ikram MA, Tiemeier H. Subjective measures of health and all-cause mortality – the Rotterdam Study. Psychol Med 2017; 47(11): 1971-1980.

Serdarevic F, Ghassabian A, Batenburg van-Eddes T, Tahirovic E, White T, Jaddoe VW, Verhulst FC, Tiemeier H. Infant neuromotor development and childhood problem behavior. Pediatrics 2017; 140(6): e20170884.

Sniekers S, Stringer S, Watanabe K, Jansen PR, Coleman JRI, Krapohl E, Taskesen E, Hammerschlag AR, Okbay A, Zabaneh D, Amin N, Breen G, Cesarini D, Chabris CF, Iacono WG, Ikram MA, Johannesson M, Koellinger P, Lee JJ, Magnusson PKE, McGue M, Miller MB, Ollier WER, Payton A, Pendleton N, Plomin R, Rietveld CA, Tiemeier H, van Duijn CM, Posthuma D. Genome-wide association meta-analysis of 78,308 individuals indentifies new loci and genes influencing human intelligence. Nat Genet 2017; 49(7): 1107-1112.

Stedehouder J, Couey JJ, Brizee D, Hosseini B, Slotman JA, Dirven CMF, Shpak G, Houtsmuller AB, Kushner SA. Fast-spiking Parvalbumin interneurons are frequently myelinated in the cerebral cortex of mice and humans. Cereb Cortex 2017; 27(10): 5001-5013.

Stedehouder J, Kushner SA. Myelination of parvalbumin interneurons: a parsimonious locus of pathophysiological convergence in schizophrenia. Mol Psychiatry 2017; 22(1): 4-12.

Swanson SA, Tiemeier H, Ikram MA, Hernan MA. Nature as a trialist? Deconstructing the analogy between Mendelian randomization and randomized trials. Epidemiology 2017; 28(5): 653-659.

Tielbeek JJ, Johansson A, Polderman TJC, Rautiainen MR, Jansen P, Taylor M, Tong X, Lu Q, Burt AS, Tiemeier H, Viding E, Plomin R, Martin NG, Heath AC, Madden PAF, Montgomery G, Beaver KM, Waldman I, Gelernter J, Kranzler HR, Farrer LA, Perry JRB, Munafò M, LoParo D, Paunio T, Tiihonen J, Mous SE, Pappa I, de Leeuw C, Watanabe K, Hammerschlag AR, Salvatore JE, Aliev F, Bigdeli TB, Dick D, Faraone SV, Popma A, Medland SE, Posthuma D; Broad Antisocial Behavior Consortium collaborators. Genome-wide association studies of a broad spectrum of antisocial behavior. JAMA Psychiatry 2017; 74(12): 1242-1250.

Vanhauwaert R, Kuenen S, Masius R, Bademosi A, Manetsberger J, Schoovaerts N, Bounti L, Gontcharenko S, Swerts J, Vilain S, Picillo M, Barone P, Munshi ST, Vrij FM de, Kushner SA, Gounko NV, Mandemakers W, Bonifati V, Meunier FA, Soukup SF, Verstreken P. The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals. EMBO J 2017; 36(10): 1392-1411.

Verdurmen MJ, Videler AC, Kamperman AM, Khasho D, Feltz-Cornelis CM van der. Cognitive behavioral therapy for somatic symptom disorders in later life: a prospective comparative explorative pilot study in two clinical populations. Neuropsychiatr Dis Treat 2017; 13: 2331-2339.

Verkaik S, Kamperman AM, Westrhenen R, Schulte PF. The treatment of premenstrual syndrome with preparations of Vitx agnus castus: a systematic review and meta-analysis. Am J Obstet Gynecol 2017; 217(2): 150-166.

Vermeiden M, Kamperman AM, Hoogendijk WJG, Broek WW van den, Birkenhager TK. A randomized clinical trial comparing two two-phase treatment strategies for in-patients with severe depression. Acta Psychiatr Scand 2017; 136(1): 118-128.

Voortman T, Keifte-de Jong JC, Ikram MA, Stricker BH, Rooij FJA van, Lahousse L, Tiemeier H, Brusselle GG, Franco OH, Schoufour JD. Adherence to the 2015 Dutch dietary guidelines and risk of non-communicable diseases and mortality in the Rotterdam Study. Eur J Epidemiol 2017; 32(11): 993-1005.

Vries AC de, Thio HB, Kort WJ de, Opmeer BC, Stok HM van der, Jong EM de, Horvath B, Busschbach JJ, Nijsten TE, Spuls PI. A prospective randomised controlled trial comparing infliximab and etanercept patient with a moderate to severe chronic plaque type psoriasis Psoriasis Infliximab versus Etanercept Comparison Evaluation, the PIECE study. Br J Dermatol 2017; 176(3): 624-633.

Wailoo AJ, Hernandez-Alava M, Manca A, Mejia A, Ray J, Crawford B, Botteman M, Busschbach JJ van. Mapping to Estimate Health-State Utility from Non-Preference-Based Outcome Measures: An ISPOR Good Practices for Outcomes Research Task Force Report. Value in Health 2017; 20 (1): 18-27.

Wesseloo R, Wierdsma AI, Kamp IL van, Munk-Olsen T, Hoogendijk WJG, Kushner SA, Bergink V. Lithium dosing strategies during pregnancy and the postpartum period. Br J Psychiatry 2017; 211(1): 31-36.

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Highlights publications 2016

Akoudad S, Aarts N, Noordam R, Ikram MA, Tiemeier H, Hofman A, Stricker BH, Vernooij MW, Visser LE. Antidepressant use is associated with an increased risk of developing microbleeds. Stroke 2016; 47(1): 251-254.

Aleknaviciute, J, Tulen JHM, Timmermans M, Rijke YB de, Rossum EFC van, Jong FH de, Kushner SA. Adrenocorticotropic hormone elicits gonadotropin secretion in premenopausal women. Hum Reprod 2016; 31(10): 2360-2368.

Bergink V, Laursen TM, Johannsen BM, Kushner SA, Meltzer-Brody S, Munk-Olsen T. Letter to the editor: Postpartum psychosis and pre-eclamptic toxaemia: a reply. Psychol Med 2016; 46(11): 2453.

Cardona Cano S, Hoek HW, Hoeken D van, Barse LM de, Jaddoe VW, Verhulst FC, Tiemeier H. Behavioral outcomes of picky eating in childhood: a prospective study in the general population. J Child Psychol Psychiatry 2016; 57(11): 1239-1246.

Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, Wellmann J, Cornelis MC, Ollila HM, Yu L, Smith JA, Pilling LC, Isaacs A, Palotie A, Zhuang WV, Zonderman A, Faul JD, Sutin A, Meirelles O, Mulas A, Hofman A, Uitterlinden A, Rivadeneira F, Perola M, Zhao W, Salomaa V, Yaffe K, Luik AI; NABEC, Liu Y, Ding J, Lichtenstein P, Landén M, Widen E, Weir DR, Llewellyn DJ, Murray A, Kardia SL, Eriksson JG, Koenen K, Magnusson PK, Ferrucci L, Mosley TH, Cucca F, Oostra BA, Bennett DA, Paunio T, Berger K, Harris TB, Pedersen NL, Murabito JM, Tiemeier H, van Duijn CM, Räikkönen K. Somatic, positive and negative domains of the center for epidemiological studies depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med 2016; 46(8): 1613-1623.

El Marroun H, Tiemeier H, Franken IH, Jaddoe VW, Lugt A van der, Verhulst FC, Lahey BB, White T. Prenatal cannabis and tobacco exposure in relation to brain morphology: a prospective neuroimaging study in young children. Biol Psychiatry 2016; 79(12): 971-979.

Florio AD, Munk-Olsen T, Bergink V. The birth of a psychiatric orphan disorder: postpartum psychosis. Lancet Psychiatry 2016; 3(6): 502.

Gazibara T, Elbert NJ, Dekker HT den, Jongste JC de, Reiss I, McGrath JJ, Eyles DW, Burne TH, Tiemeier H, Jaddoe VW, Pasmans SG, Duijts L. Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood eczema. The Generation R study. Pediatr Allergy Immunol 2016; 27(3): 283-289.

Gouty-Colomer LA, Hosseini B, Marcelo IM, Schreiber J, Slump DE, Yamaguchi S, Houweling AR, Jaarsma D, Elgersma Y, Kushner SA. Arc expression identifies the lateral amygdala fear memory trace. Mol Psychiatry 2016; 21(3): 364-375.

Guxens M, Ghassabian A, Gong T, Garcia-Esteban R, Porta D, Giorgis-Allemand L, Almqvist C, Aranbarri A, Beelen R, Badaloni C, Cesaroni G, de Nazelle A, Estarlich M, Forastiere F, Forns J, Gehring U, Ibarluzea J, Jaddoe VW, Korek M, Lichtenstein P, Nieuwenhuijsen MJ, Rebagliato M, Slama R, Tiemeier H, Verhulst FC, Volk HE, Pershagen G, Brunekreef B, Sunyer J. Air pollution exposure during pregnancy and childhood autistic traits in four European population-based cohort studies: the ESCAPE project. Environ Health Perspect 2016; 1: 133-140.

Jiskoot LC, Dopper EG, Heijer TD, Timman R, Minkelen R van, Swieten JC van, Papma JM. Presymptomatic cognitive decline in familial frontotemporal dementia: a longitudinal study. Neurology 2016; 87(4): 384-391.

Johannsen BM, Larsen JT, Laursen TM, Bergink V, Meltzer-Brody S, Munk-Olsen T. All-cause mortality in women with severe postpartum psychiatric disorders. Am J Psychiatry 2016; 173(6): 635-642.

Jones SE, Tyrrell J, Wood AR, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Teder-Laving M, Hayward C, Reonneberg T, Wilson JF, Del Greco F, Hicks AA, Shin C, Yun CH, Lee SK, Metspalu A, Byrne EM, Gehrman PR, Tiemeier H, Allebrandt KV, Freathy RM, Murray A, Hinds DA, Frayling TM, Weedon MN. Genome-wide association analyses in 128,266 individuals identifies new morningness and sleep duration. PLoS Genet 2016; 12(8): e1006125.

Jong MH de, Kamperman AM, Mulder CL. Open wards in psychiatric clinics and compulsory psychiatric admissions – Reply. JAMA Psychiatry 2016; 73(12): 1293-1294.

Jong MH de, Kamperman AM, Oorschot M, Priebe S, Bramer W, Sande R van de, Van Gool AR, Mulder CL. Intervention to reduce compulsory psychiatric admissions: a systematic review and meta-analysis. JAMA Psychiatry 2016; 73(7): 657-664.

Joubert BR, Dekker HT den, Felix JF, Bohlin J, Ligthart S, Beckett E, Tiemeier H, Meurs JB van, Uitterlingen AG, Hofman A, Haberg SE, Reese SE, Peters MJ, Kulle Andreassen B, Steegers EA, Nilsen RM, Vollset SE, Midttun O, Ueland PM, Franco OH, Dehghan A, Jongste JC de, Wu MC, Wang T, Peddada SD, Jaddoe VW, Nystad W, Duijts L, London SJ. Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns. Nat Commun 2016; 7: 10577.

Jovanova O, Luik AI, Leening MJ, Noordam R, Aarts N, Hofman A, Franco OH, Dehghan A, Tiemeier H. Th long-term risk of recognized and unrecognized myocardial infarction for depression in older men. Psychol Med 2016; 46(9): 1951-1960.

Medema S, Mocking RJ, Koeter MW, Vaz FM, Meijer C, Haan L de, Beveren NJ van, for GROUP. Levels of red blood cell fatty acids in patients with psychosis, their unaffected siblings, and healthy controls. Schizophr Bull 2016; 42(2): 358-368.

Middeldorp CM, Hammerschlag AR, Ouwens KG, Groen-Blokhuis MM, St Pourcain B, Greven CU, Pappa I, Tiesler CM, Ang W, Nolte IM, Vilor-Tejedor N, Bacelis J, Ebejer JL, Zhao H, Davies GE, Ehli EA, Evans DM, Fedko IO, Guxens M, Hottenga JJ, Hudziak JJ, Jugessur A, Kemp JP, Krapohl E, Martin NG, Murcia M, Myhre R, Ormel J, Ring SM, Standl M, Stergiakouli E, Stoltenberg C, Thiering E, Timpson NJ, Trzaskowski M, van der Most PJ, Wang C; EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortium, Psychiatric Genomics Consortium ADHD Working Group, Nyholt DR, Medland SE, Neale B, Jacobsson B, Sunyer J, Hartman CA, Whitehouse AJ, Pennell CE, Heinrich J, Plomin R, Davey Smith G, Tiemeier H, Posthuma D, Boomsma DI. A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts. J Am Acad Child Adolesc Psychiatry 2016; 55(10): 896-905.

Mirza SS, Bruijn RF de, Koudstaal PJ, Meiracker AH van den, Franco OH, Hofman A, Tiemeier H, Ikram MA. The N-terminal pro B-type natriuretic peptide, and risk of dementia and cognitive decline: a 10-year follow-up study in the general population. J Neurol Neurosurg Psychiatry 2016; 87(4): 356-362.

Mirza SS, Wolters FJ, Swanson SA, Koudstaal PJ, Hofman A, Tiemeier H, Ikram MA. 10-year trajectories of depressive symptoms and risk of dementia: a population-based study. Lancet Psychiatry 2016; 3(7): 628-635.

Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonzalez JR, Haitjema S, Karlsson R, van der Laan SW, Ladwig KH, Lahti J, van der Lee SJ, Lind PA, Liu T, Matteson L, Mihailov E, Miller MB, Minica CC, Nolte IM, Mook-Kanamori D, van der Most PJ, Oldmeadow C, Qian Y, Raitakari O, Rawal R, Realo A, Rueedi R, Schmidt B, Smith AV, Stergiakouli E, Tanaka T, Taylor K, Wedenoja J, Wellmann J, Westra HJ, Willems SM, Zhao W; LifeLines Cohort Study, Amin N, Bakshi A, Boyle PA, Cherney S, Cox SR, Davies G, Davis OS, Ding J, Direk N, Eibich P, Emeny RT, Fatemifar G, Faul JD, Ferrucci L, Forstner A, Gieger C, Gupta R, Harris TB, Harris JM, Holliday EG, Hottenga JJ, De Jager PL, Kaakinen MA, Kajantie E, Karhunen V, Kolcic I, Kumari M, Launer LJ, Franke L, Li-Gao R, Koini M, Loukola A, Marques-Vidal P, Montgomery GW, Mosing MA, Paternoster L, Pattie A, Petrovic KE, Pulkki-Råback L, Quaye L, Räikkönen K, Rudan I, Scott RJ, Smith JA, Sutin AR, Trzaskowski M, Vinkhuyzen AE, Yu L, Zabaneh D, Attia JR, Bennett DA, Berger K, Bertram L, Boomsma DI, Snieder H, Chang SC, Cucca F, Deary IJ, van Duijn CM, Eriksson JG, Bültmann U, de Geus EJ, Groenen PJ, Gudnason V, Hansen T, Hartman CA, Haworth CM, Hayward C, Heath AC, Hinds DA, Hyppönen E, Iacono WG, Järvelin MR, Jöckel KH, Kaprio J, Kardia SL, Keltikangas-Järvinen L, Kraft P, Kubzansky LD, Lehtimäki T, Magnusson PK, Martin NG, McGue M, Metspalu A, Mills M, de Mutsert R, Oldehinkel AJ, Pasterkamp G, Pedersen NL, Plomin R, Polasek O, Power C, Rich SS, Rosendaal FR, den Ruijter HM, Schlessinger D, Schmidt H, Svento R, Schmidt R, Alizadeh BZ, Sørensen TI, Spector TD, Steptoe A, Terracciano A, Thurik AR, Timpson NJ, Tiemeier H, Uitterlinden AG, Vollenweider P, Wagner GG, Weir DR, Yang J, Conley DC, Smith GD, Hofman A, Johannesson M, Laibson DI, Medland SE, Meyer MN, Pickrell JK, Esko T, Krueger RF, Beauchamp JP, Koellinger PD, Benjamin DJ, Bartels M, Cesarini D. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016; 48(6): 624-633.

Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Concas M, Derringer J, Furlotte NA, Galesloot TE, Girotto G, Gupta R, Hall LM, Harris SE, Hofer E, Horikoshi M, Huffman JE, Kaasik K, Kalafati IP, Karlsson R, Kong A, Lahti J, van der Lee SJ, deLeeuw C, Lind PA, Lindgren KO, Liu T, Mangino M, Marten J, Mihailov E, Miller MB, van der Most PJ, Oldmeadow C, Payton A, Pervjakova N, Peyrot WJ, Qian Y, Raitakari O, Rueedi R, Salvi E, Schmidt B, Schraut KE, Shi J, Smith AV, Poot RA, St Pourcain B, Teumer A, Thorleifsson G, Verweij N, Vuckovic D, Wellmann J, Westra HJ, Yang J, Zhao W, Zhu Z, Alizadeh BZ, Amin N, Bakshi A, Baumeister SE, Biino G, Bønnelykke K, Boyle PA, Campbell H, Cappuccio FP, Davies G, De Neve JE, Deloukas P, Demuth I, Ding J, Eibich P, Eisele L, Eklund N, Evans DM, Faul JD, Feitosa MF, Forstner AJ, Gandin I, Gunnarsson B, Halldórsson BV, Harris TB, Heath AC, Hocking LJ, Holliday EG, Homuth G, Horan MA, Hottenga JJ, de Jager PL, Joshi PK, Jugessur A, Kaakinen MA, Kähönen M, Kanoni S, Keltigangas-Järvinen L, Kiemeney LA, Kolcic I, Koskinen S, Kraja AT, Kroh M, Kutalik Z, Latvala A, Launer LJ, Lebreton MP, Levinson DF, Lichtenstein P, Lichtner P, Liewald DC; LifeLines Cohort Study, Loukola A, Madden PA, Mägi R, Mäki-Opas T, Marioni RE, Marques-Vidal P, Meddens GA, McMahon G, Meisinger C, Meitinger T, Milaneschi Y, Milani L, Montgomery GW, Myhre R, Nelson CP, Nyholt DR, Ollier WE, Palotie A, Paternoster L, Pedersen NL, Petrovic KE, Porteous DJ, Räikkönen K, Ring SM, Robino A, Rostapshova O, Rudan I, Rustichini A, Salomaa V, Sanders AR, Sarin AP, Schmidt H, Scott RJ, Smith BH, Smith JA, Staessen JA, Steinhagen-Thiessen E, Strauch K, Terracciano A, Tobin MD, Ulivi S, Vaccargiu S, Quaye L, van Rooij FJ, Venturini C, Vinkhuyzen AA, Völker U, Völzke H, Vonk JM, Vozzi D, Waage J, Ware EB, Willemsen G, Attia JR, Bennett DA, Berger K, Bertram L, Bisgaard H, Boomsma DI, Borecki IB, Bültmann U, Chabris CF, Cucca F, Cusi D, Deary IJ, Dedoussis GV, van Duijn CM, Eriksson JG, Franke B, Franke L, Gasparini P, Gejman PV, Gieger C, Grabe HJ, Gratten J, Groenen PJ, Gudnason V, van der Harst P, Hayward C, Hinds DA, Hoffmann W, Hyppönen E, Iacono WG, Jacobsson B, Järvelin MR, Jöckel KH, Kaprio J, Kardia SL, Lehtimäki T, Lehrer SF, Magnusson PK, Martin NG, McGue M, Metspalu A, Pendleton N, Penninx BW, Perola M, Pirastu N, Pirastu M, Polasek O, Posthuma D, Power C, Province MA, Samani NJ, Schlessinger D, Schmidt R, Sørensen TI, Spector TD, Stefansson K, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Tung JY, Uitterlinden AG, Vitart V, Vollenweider P, Weir DR, Wilson JF, Wright AF, Conley DC, Krueger RF, Davey Smith G, Hofman A, Laibson DI, Medland SE, Meyer MN, Yang J, Johannesson M, Visscher PM, Esko T, Koellinger PD, Cesarini D, Benjamin DJ. Genome-wide association study identifies 74 loci associated with educational attainment. Nature 2016; 533(7604): 539-542.

Olgiati S, Quadri M, Fang M, Rood JP, Saute JA, Fen Chien H, Bouwkamp CG, Graafland J, Minneboo M, Breedveld GJ, Zhang J; International Parkinsonism Genetics Network, Verheijen FW, Boon AJ, Kievit AJ, Jardim LB, Mandemakers W, Barbosa ER, Rieder CR, Leenders KL, Wang J, Bonifati V. DNAJC6 mutations associated with early-onset Parkinson′s disease. Ann Neurol 2016; 79(2): 244-256.

Otowa T, Hek K, Lee M, Byrne EM, Mirza SS, Nivard MG, Bigdeli T, Aggen SH, Adkins D, Wolen A, Fanous A, Keller MC, Castelao E, Kutalik Z, der Auwera SV, Homuth G, Nauck M, Teumer A, Milaneschi Y, Hottenga JJ, Direk N, Hofman A, Uitterlinden A, Mulder CL, Henders AK, Medland SE, Gordon S, Heath AC, Madden PA, Pergadia ML, van der Most PJ, Nolte IM, van Oort FV, Hartman CA, Oldehinkel AJ, Preisig M, Grabe HJ, Middeldorp CM, Penninx BW, Boomsma D, Martin NG, Montgomery G, Maher BS, van den Oord EJ, Wray NR, Tiemeier H, Hettema JM. Meta-analysis of genome-wide association studies of anxiety disorders. Mol Psychiatry 2016; 21(10): 1391-1399.

Peter S, Ten Brinke MM, Stedehouder J, Reinelt CM, Wu B, Zhou H, Zhou K, Boele HJ, Kushner SA, Lee MG, Schmeisser MJ, Boeckers TM, Schonewille M, Hoebeek FE, Zeeuw CI de. Dysfunctional cerebellar Purkinje cells contribute to autism-like behavior in Shank2-deficient mice. Nat Commun 2016; 7: 12627.

Portegies ML, Bos MJ, Koudstaal PJ, Hofman A, Tiemeier HW, Ikram MA. Anxiety and the risk of stroke: the Rotterdam Study. Stroke 2016; 47(4): 1120-1123.

Rijlaarsdam J, Tiemeier H, Ringoot AP, Ivanova MY, Jaddoe VW, Verhulst FC, Roza SJ. Early family regularity protects against later disruptive behavior. Eur Child Adolesc Psychiatry 2016; 25(7): 781-789.

Rucci E, Dekker HT den, Jongste JC de, Steenweg-de Graaff J, Gaillard R, Pasmans SG, Hofman A, Tiemeier H, Jaddoe VW, Duijts L. Maternal Fatty acid levels during pregnancy, childhood lung function and atopic diseases. The Generation R study. Clin Exp Allergy 2016; 46(3): 461-471.

Schmaal L, Veltman DJ, van Erp TG, Sämann PG, Frodl T, Jahanshad N, Loehrer E, Tiemeier H, Hofman A, Niessen WJ, Vernooij MW, Ikram MA, Wittfeld K, Grabe HJ, Block A, Hegenscheid K, Völzke H, Hoehn D, Czisch M, Lagopoulos J, Hatton SN, Hickie IB, Goya-Maldonado R, Krämer B, Gruber O, Couvy-Duchesne B, Rentería ME, Strike LT, Mills NT, de Zubicaray GI, McMahon KL, Medland SE, Martin NG, Gillespie NA, Wright MJ, Hall GB, MacQueen GM, Frey EM, Carballedo A, van Velzen LS, van Tol MJ, van der Wee NJ, Veer IM, Walter H, Schnell K, Schramm E, Normann C, Schoepf D, Konrad C, Zurowski B, Nickson T, McIntosh AM, Papmeyer M, Whalley HC, Sussmann JE, Godlewska BR, Cowen PJ, Fischer FH, Rose M, Penninx BW, Thompson PM, Hibar DP. Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder Working group. Mol Psychiatry 2016; 21(6): 806-812.

Steenweg-de Graaff J, Tiemeier H, Ghassabian A, Rijlaarsdam J, Jaddoe VW, Verhulst FC, Roza SJ. Maternal fatty acid status during pregnancy and child autistic traits: The Generation R Study. Am J Epidemiol 2016; 183(9): 792-799.

Vreeker A, Boks MP, Abramovic L, Verkooijen S, Bergen AH van, Hillegers MH, Spijker AT, Hoencamp E, Regeer EJ, Riemersma-van der Lek RF, Stevens AW, Schulte PF, Vonk R, Hoekstra R, Beveren NJ van, Kupka RW, Brouwer RM, Bearden CE, MacCabe JH, Ophoff RA, GROUP Investigators. High educational performance is a distinctive feature of bipolar disorder: a study on cognition in bipolar disorder, schizophrenia patients, relatives and controls. Psychol Med 2016; 46(4): 807-818.

Visser MM, Heijenbrok-Kal MH, Spijker A van ‘t, Lannoo E, Busschbach JJ, Ribbers GM. Problem-solving therapy during outpatient stroke rehabilitation improves coping and health-related quality of life: randomized controlled trial. Stroke 2016; 47(1): 135-142.

Wesseloo R, Kamperman AM, Munk-Olsen T, Pop VJ, Kushner SA, Bergink V. Risk of postpartum relapse in bipolar disorder and postpartum psychosis: a systematic review and meta-analysis. Am J Psychiatry 2016; 173(2): 117-127.

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Highlights publications 2015

Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC (including Hoogendijk W). Genetic differences in the immediate transcriptome response to stress predict risk-related brain function and psychiatric disorders. Neuron 2015; 86(5): 1189-1202.

Berg WE van den, Lamballais S, Kushner SA. Sex-specific mechanism of social hierarchy in mice. Neuropsychopharmacology 2015; 40(6): 1364-1372.

Bergink V, Armangue T, Titulaer MJ, Markx S, Dalmau J, Kushner SA. Autoimmune encephalitis in postpartum psychosis. Am J Psychiatry 2015; 172(9): 901-908.

Bergink V, Burgerhout KM, Koorengevel KM, Kamperman AM, Hoogendijk WJ, Lambregtse-van den Berg MP, Kushner SA. Treatment of psychosis and mania in the postpartum period. Am J Psychiatry 2015; 172(2): 115-123.

Bergink V, Gibney SM, Drexhage HA. Autoimmunity, inflammation and psychosis: a search for peripheral markers. Biological Psychiatry 2014; 75(4): 324-331.

Bergink V, Kushner SA. Lithium during pregnancy. Am J Psychiatry 2014; 171(7): 712-715.

Bergink V, Laursen TM, Johannsen BM, Kushner SA, Meltzer-Brody S, Munk-Olsen T. Pre-eclempsia and first-onset postpartum psychiatric episodes: a Danish population-based cohort study. Psychol Med 2015; 45(16): 3481-3489.

The Coffee and Caffeine Genetics Consortium, Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, Teumer A, Yu K, Marques-Vidal P, Rawal R, Manichaikul A, Wojczynski MK, Vink JM, Zhao JH, Burlutsky G, Lahti J, Mikkilä V, Lemaitre RN, Eriksson J, Musani SK, Tanaka T, Geller F, Luan J, Hui J, Mägi R, Dimitriou M, Garcia ME, Ho W-K, Wright MJ, Rose LM, Magnusson PKE, Pedersen NL, Couper D, Oostra BA, Hofman A, Ikram MA, Tiemeier HW, Uitterlinden AG, Rooij FJA van, Barroso I, Johansson I, Xue L, Kaakinen M, Milani L, Power C, Snieder H, Stolk RP, Baumeister SE, Biffar R, Gu F, Bastardot F, Kutalik Z, Jacobs Jr DR, Forouhi NG, Mihailov E, Lind L, Lindgren C, Michaëlsson K, Morris A, Jensen M, Khaw K-T, Luben RN, Wang JJ, Männistö S, Perälä M-M, Kähönen M, Lehtimäki T, Viikari J, Mozaffarian D, Mukamal K, Psaty BM, Döring A, Heath AC, Montgomery GW, Dahmen N, Carithers T, Tucker KL, Ferrucci L, Boyd HA, Melbye M, Treur JL, Mellström D, Hottenga JJ, Prokopenko I, Tönjes A, Deloukas P, Kanoni S, Lorentzon M, Houston DK, Liu Y, Danesh J, Rasheed A, Mason MA, Zonderman AB, Franke L, Kristal BS, International Parkinson′s Disease Genomics Consortium (IPDGC), North American Brain Expression Consortium (NABEC), UK Brain Expression Consortium (UKBEC), Karjalainen J, Reed DR, Westra H-J, Evans MK, Saleheen D, Harris TB, Dedoussis G, Curhan G, Stumvoll M, Beilby J, Pasquale LR, Feenstra B, Bandinelli S, Ordovas JM, Chan AT, Peters U, Ohlsson C, Gieger C, Martin NG, Waldenberger M, Siscovick DS, Raitakari O, Eriksson JG, Mitchell P, Hunter DJ, Kraft P, Rimm EB, Boomsma DI, Borecki IB, Loos RJF, Wareham NJ, Vollenweider P, Caporaso N, Grabe HJ, Neuhouser ML, Wolffenbuttel BHR, Hu FB, Hyppönen E, Järvelin M-R, Cupples LA, Franks PW, Ridker PM, Duijn CM van, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, Dam RM van, Chasman Channing DI. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry 2015; 20(5): 647-656.

Denee TR, Geerts P, Sermon J, Decuypere F, Widrich C, Rijntjes R, Mulder CL. Treatment continuation and treatment characteristics of four long acting antipsychotic medications (Paliperidone Palmitate, Risperidone Microspheres, Olanzapine Pamoate and Haloperidol Decanoate) in The Netherlands. Value Health 2015; 18(7): A407.

Gameiro S, Boivin J, Dancet E, Klerk C de, Emery M, Lewis-Jones C, Thorn P, Broeck U van den, Venetis C, Verhaak CM, Wischmann T, Vermeulen N. ESHRE guideline: routine psychosocial care in infertility and medically assisted reproduction – a guide for fertility staff. Hum Reprod 2015; 30(11): 2476-2485.

Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, Evans DS, Grabe HJ, Lahti J, Li M, Lehtimäki T, Lumley T, Marciante KD, Pérusse L, Psaty BM, Robbins J, Tranah GJ, Vink JM, Wilk JB, Stafford JM, Bellis C, Biffar R, Bouchard C, Cade B, Curhan GC, Eriksson JG, Ewert R, Ferrucci L, Fülöp T, Gehrman PR, Goodloe R, Harris TB, Heath AC, Hernandez D, Hofman A, Hottenga JJ, Hunter DJ, Jensen MK, Johnson AD, Kähönen M, Kao L, Kraft P, Larkin EK, Lauderdale DS, Luik AI, Medici M, Montgomery GW, Palotie A, Patel SR, Pistis G, Porcu E, Quaye L, Raitakari O, Redline S, Rimm EB, Rotter JI, Smith AV, Spector TD, Teumer A, Uitterlinden AG, Vohl MC, Widen E, Willemsen G, Young T, Zhang X, Liu Y, Blangero J, Boomsma DI, Gudnason V, Hu F, Mangino M, Martin NG, O′Connor GT, Stone KL, Tanaka T, Viikari J, Gharib SA, Punjabi NM, Räikkönen K, Völzke H, Mignot E, Tiemeier H. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Mol Psychiatry 2015; 20(10): 1232-1239.

Hofman A, Brusselle GG, Murad SD, Duijn CM van, Franco OH, Goedegedure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol 2015; 30(8): 661-708.

Ibrahimi K, Oosterhout WP van, Dorp W van, Danser AH, Garrelds IM, Kushner SA, Lesaffre EM, Terwindt GM, Ferrari MD, Meiracker AH van den, Maassen VanDenBrink A. Reduced trigeminovascular cyclicity in patients with menstrually related migraine. Neurology 2015; 84(2): 125-131.

Ismail SY, Duerinckx N, Knoop MM van der, Timmerman L, Weimar W, Dobbles F, Massay EK, Busschbach JJ van. Toward a conceptualization of the content of psychosocial screening in living organ donors: an ethical legal psychological aspects of transplantation concensus. Transplantation 2015; 99 (11):2413-242.

Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stančáková A, Faul JD, Zhao W, Bartz TM, Concas MP, Franceschini N, Enroth S, Vitart V, Trompet S, Guo X, Chasman DI, O'Connel JR, Corre T, Nongmaithem SS, Chen Y, Mangino M, Ruggiero D, Traglia M, Farmaki AE, Kacprowski T, Bjonnes A, van der Spek A, Wu Y, Giri AK, Yanek LR, Wang L, Hofer E, Rietveld CA, McLeod O, Cornelis MC, Pattaro C, Verweij N, Baumbach C, Abdellaoui A, Warren HR, Vuckovic D, Mei H, Bouchard C, Perry JR, Cappellani S, Mirza SS, Benton MC, Broeckel U, Medland SE, Lind PA, Malerba G, Drong A, Yengo L, Bielak LF, Zhi D, van der Most PJ, Shriner D, Mägi R, Hemani G, Karaderi T, Wang Z, Liu T, Demuth I, Zhao JH, Meng W, Lataniotis L, van der Laan SW, Bradfield JP, Wood AR, Bonnefond A, Ahluwalia TS, Hall LM, Salvi E, Yazar S, Carstensen L, de Haan HG, Abney M, Afzal U, Allison MA, Amin N, Asselbergs FW, Bakker SJ, Barr RG, Baumeister SE, Benjamin DJ, Bergmann S, Boerwinkle E, Bottinger EP, Campbell A, Chakravarti A, Chan Y, Chanock SJ, Chen C, Chen YI, Collins FS, Connell J, Correa A, Cupples LA, Smith GD, Davies G, Dörr M, Ehret G, Ellis SB, Feenstra B, Feitosa MF, Ford I, Fox CS, Frayling TM, Friedrich N, Geller F, Scotland G, Gillham-Nasenya I, Gottesman O, Graff M, Grodstein F, Gu C, Haley C, Hammond CJ, Harris SE, Harris TB, Hastie ND, Heard-Costa NL, Heikkilä K, Hocking LJ, Homuth G, Hottenga JJ, Huang J, Huffman JE, Hysi PG, Ikram MA, Ingelsson E, Joensuu A, Johansson Å, Jousilahti P, Jukema JW, Kähönen M, Kamatani Y, Kanoni S, Kerr SM, Khan NM, Koellinger P, Koistinen HA, Kooner MK, Kubo M, Kuusisto J, Lahti J, Launer LJ, Lea RA, Lehne B, Lehtimäki T, Liewald DC, Lind L, Loh M, Lokki ML, London SJ, Loomis SJ, Loukola A, Lu Y, Lumley T, Lundqvist A, Männistö S, Marques-Vidal P, Masciullo C, Matchan A, Mathias RA, Matsuda K, Meigs JB, Meisinger C, Meitinger T, Menni C, Mentch FD, Mihailov E, Milani L, Montasser ME, Montgomery GW, Morrison A, Myers RH, Nadukuru R, Navarro P, Nelis M, Nieminen MS, Nolte IM, O'Connor GT, Ogunniyi A, Padmanabhan S, Palmas WR, Pankow JS, Patarcic I, Pavani F, Peyser PA, Pietilainen K, Poulter N, Prokopenko I, Ralhan S, Redmond P, Rich SS, Rissanen H, Robino A, Rose LM, Rose R, Sala C, Salako B, Salomaa V, Sarin AP, Saxena R, Schmidt H, Scott LJ, Scott WR, Sennblad B, Seshadri S, Sever P, Shrestha S, Smith BH, Smith JA, Soranzo N, Sotoodehnia N, Southam L, Stanton AV, Stathopoulou MG, Strauch K, Strawbridge RJ, Suderman MJ, Tandon N, Tang ST, Taylor KD, Tayo BO, Töglhofer AM, Tomaszewski M, Tšernikova N, Tuomilehto J, Uitterlinden AG, Vaidya D, van Hylckama Vlieg A, van Setten J, Vasankari T, Vedantam S, Vlachopoulou E, Vozzi D, Vuoksimaa E, Waldenberger M, Ware EB, Wentworth-Shields W, Whitfield JB, Wild S, Willemsen G, Yajnik CS, Yao J, Zaza G, Zhu X; BioBank Japan Project, Salem RM, Melbye M, Bisgaard H, Samani NJ, Cusi D, Mackey DA, Cooper RS, Froguel P, Pasterkamp G, Grant SF, Hakonarson H, Ferrucci L, Scott RA, Morris AD, Palmer CN, Dedoussis G, Deloukas P, Bertram L, Lindenberger U, Berndt SI, Lindgren CM, Timpson NJ, Tönjes A, Munroe PB, Sørensen TI, Rotimi CN, Arnett DK, Oldehinkel AJ, Kardia SL, Balkau B, Gambaro G, Morris AP, Eriksson JG, Wright MJ, Martin NG, Hunt SC, Starr JM, Deary IJ, Griffiths LR, Tiemeier H, Pirastu N, Kaprio J, Wareham NJ, Pérusse L, Wilson JG, Girotto G, Caulfield MJ, Raitakari O, Boomsma DI, Gieger C, van der Harst P, Hicks AA, Kraft P, Sinisalo J, Knekt P, Johannesson M, Magnusson PK, Hamsten A, Schmidt R, Borecki IB, Vartiainen E, Becker DM, Bharadwaj D, Mohlke KL, Boehnke M, van Duijn CM, Sanghera DK, Teumer A, Zeggini E, Metspalu A, Gasparini P, Ulivi S, Ober C, Toniolo D, Rudan I, Porteous DJ, Ciullo M, Spector TD, Hayward C, Dupuis J, Loos RJ, Wright AF, Chandak GR, Vollenweider P, Shuldiner AR, Ridker PM, Rotter JI, Sattar N, Gyllensten U, North KE, Pirastu M, Psaty BM, Weir DR, Laakso M, Gudnason V, Takahashi A, Chambers JC, Kooner JS, Strachan DP, Campbell H, Hirschhorn JN, Perola M, Polašek O, Wilson JF. Directional dominance on stature and cognition in diverse human populations. Nature 2015; 523(7561): 459-462.

Karyotaki E, Kleiboer A, Smit F, Turner DT, Pastor AM, Andersson G, Berger T, Botella C, Breton JM, Carlbring P, Christensen H, Graaf E de, Griffiths K, Donker T, Farrer L, Huibers MJ, Lenndin J, Mackinnon A, Meyer B, Moritz S, Riper H, Spek V, Vernmark K, Cuijpers P. Predictors of treatment dropout in self-guided web-based interventions for depression: an 'individual patient data' meta-analysis. Psychol Med 2015;45(13):2717-2726.

Kok R, Thijssen S, Bakermans-Kranenburg MJ, Jaddoe VW, Verhulst FC, White T, IJzendoorn MH van, Tiemeier H. Normal variation in early parental sensitivity predicts child structural brain development. J Am Acad Child Adolesc Psychiatry 2015; 54(10): 824-831.

Luijk MP, Sonnenschein-van der Voort AMM, Mileva-Seitz VR, Jansen PW, Verhulst FC, Hofman A, Jaddoe VWV, Jongste JC de, IJzendoorn MH van, Duijts L, Tiemeier H. Is parent-child bed-sharing a risk for wheezing and asthma in early childhood? Eur Respir J 2015; 45(3): 661-669.

Maier R, Moser G, Chen GB, Ripke S, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Coryell W, Potash JB, Scheftner WA, Shi J, Weissman MM, Hultman CM, Landen M, Levinson DF, Kendler KS, Smoller JW, Wray NR, Lee SH; Cross-Disorder Working Group of the Psychiatric Genomics Consortium (including Hoogendijk W). Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. Am J Hum Genet 2015; 96(2): 283-294.

Massey EK, Tielen M, Laging M, Timman R, Beck DK, Khemai R, Gelder T van, Weimar W. Discrepanties between beliefs and behavior: a prospective study into immunosuppressive medication adherence after kidney transplantation. Transplantation 2015; 99(2): 375-380.

Mil NH van, Steegers-Theunissen RP, Motazedi E, Jansen PW, Jaddoe VW, Steegers EA, Verhulst FC, Tiemeier H. Low and high birth weight and the risk of child attention problems. J Pediatr 2015; 166(4): 862-869.

Mirza SS, Ikram MA, Hofman A, Tiemeier H. Anxiety does not predict mortality: a population-based study. World Psychiatry 2015; 14(1): 103-104.

Modesto T, Tiemeier H, Peeters RP, Jaddoe VW, Hofman A, Verhulst FC, Ghassabian A. Maternal mild thyroid hormone insufficiency in early pregnancy and attention-deficit/hyperactivity disorder symptoms in children. JAMA Pediatr 2015; 169(9): 838-845.

Mous SE, Hammerslchlag AR, Polderman TJ, Verhulst FC, Tiemeier H, Lugt A van der, Jaddoe VW, Hofman A, White T, Posthuma D. A population-based imaging genetics study of inattention/hyperactivity: basal ganglia and genetic pathways. J Am Acad Child Adolesc Psychiatry 2015; 54(9): 745-752.

Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium (incl Hoogendijk W). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci 2015; 18(2): 199-209.

Offerman MP, Pruyn JF, Boer MF de, Busschbach JJ, Baatenburg de Jong RJ. Psychosocial consequences for partners of patients after total laryngectomy and for the relationship between patients and partners. Oral Oncol 2015; 51(4): 389-398.

Okray Z, Esch CE de, Esch H van, Devriendt K, Claeys A, Yan J, Verbeeck J, Froyen G, Willemsen R, Vrij FM de, Hassan BA. A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function. EMBO Mol Med 2015; 7(4): 423-437.

Omrani A, Vaart T van der, Mientjes E, Woerden GM van, Hojjati MR, Li KW, Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y. HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1. Mol Psychiatry 2015; 20(11): 1311-1321.

Pappa I, Mileva-Seitz VR, Bakermans-Kranenburg MJ, Tiemeier H, IJzendoorn MH. The magnificant seven: a quantitative review of dopamine receptor D4 and its association with child behavior. Neurosci Biobehav Rev 2015; 57: 175-186.

Pessoa BS, Slump DE, Ibrahimi K, Grefhorst A, Veghel R van, Garrelds IM, Roks AJ, Kushner SA, Danser AH, Esch JH van. Angiotensin II type 2 receptor- and acetylcholine-mediated relaxation: essential contribution of female sex hormones and chromosomes. Hypertension 2015; 66(2): 396-402.

Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S; Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium (Corporate Collaborator), Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J; Social Science Genetic Association Consortium (Corporate Collaborator), Willemsen G, Zhu Z, Boomsma DI, Wray NR, Penninx BW; Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium Corporate Collaborator; Social Science Genetic Association Consortium Corporate Collaborator (including Hoogendijk W, Tiemeier H). The association between lower educational attainment and depression owing to shared genetic effects? Results in 25000 subjects. Mol Psychiatry 2015; 20(6): 735-743.

Rijlaarsdam J, Stevens GW, Ende J van der, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Prevalence of DSM-IV disorders in a population-based sample of 5- to 8-year-old children: the impact of impairment criteria.Eur Child Adolesc Psychiatry 2015; 24(11): 1339-1348.

Saavedra Perez HC, Ikram MA, Direk N, Prigerson HG, Freak-Poli R, Verhaaren BF, Hofman A, Vernooij M, Tiemeier H. Cognition, structural brain changes and complicated grief. A population-based study. Psychol Med 2015; 45(7): 1389-1399.

Sajjad A, Mirza SS, Portegies MLP, Bos MJ, Hofman A, Koudstaal PJ, Tiemeier H, Ikram MA. Subjective memory complaints and the risk of stroke. Stroke 2015; 46(1): 170-175.

Silva-Santos S, Woerden GM van, Bruinsma CF, Mientjes E, Jolfaei MA, Distel B, Kushner SA, Elgersma Y. Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model. J Clin Invest 2015; 125(5): 2069-2076.

Staphorst M, Vathorst SV. Empirical Data on Benefits Children Experience in Clinical Research. Am J Bioeth 2015 Nov;15(11):20-21.

Timman R, Bouwmans C, Busschbach JJ van, Hakkaart Roijen L van. Development of the Treatment Inventory of Costs in Psychiatric Patients: TIC-P Mini and Midi. Value Health 2015 Dec;18(8):994-999.

Timmerman L, Laging M, Westerhof GJ, Timman R, Zuidema WC, Beck DK, IJzermans JN, Betjes MG, Busschbach JJ, Weimar W, Massey EK. Mental health among living kidney donors: a prospective comparison with matched controls from the general population. Am J Transplant 2015; 15(2): 508-517.

Verlinden M, Jansen PW, Veenstra R, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Preschool Attention-Deficit/Hyperactivity and oppositional defiant problems as antecedents of school bullying. J Am Acad Child Adolesc Psychiatry 2015; 54(7): 571-579.

Visser MS, Zonneveld LN, Spijker A van ‘t, Hunink MG, Busschbach JJ. The cost-effectiveness of cognitive-behavioral group training for patients with unexplained physical symptoms. Value Health 2015; 18(5): 570-577.

Witte de LD, Hoffmann C, Mierlo HC van, Titulaer MJ, Kahn RS, Martinez-Martinez P, European Consortium of Autoimmune Mental Disorders (CAIMED) (including Beveren NJ van, Roder CH). Absence of N-Methyl-D-Aspartate receptor IgG autoantibodies in schizophrenia: the importance of cross-validation studies. JAMA Psychiatry 2015; 72(7): 731-733.

Zimmermann E, Ängquist LH, Mirza SS, Zhao JH, Chasman DI, Fischer K, Qi Q, Smith AV, Thinggaard M, Jarczok MN, Nalls MA, Trompet S, Timpson NJ, Schmidt B, Jackson AU, Lyytikäinen LP, Verweij N, Mueller-Nurasyid M, Vikström M, Marques-Vidal P, Wong A, Meidtner K, Middelberg RP, Strawbridge RJ, Christiansen L; FTO-Mortality Collaborating Group, Kyvik KO, Hamsten A, Jääskeläinen T, Tjønneland A, Eriksson JG, Whitfield JB, Boeing H, Hardy R, Vollenweider P, Leander K, Peters A, van der Harst P, Kumari M, Lehtimäki T, Meirhaeghe A, Tuomilehto J, Jöckel KH, Ben-Shlomo Y, Sattar N, Baumeister SE, Davey Smith G, Casas JP, Houston DK, März W, Christensen K, Gudnason V, Hu FB, Metspalu A, Ridker PM, Wareham NJ, Loos RJ, Tiemeier H, Sonestedt E, Sørensen TI. Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169.551 Caucasian adults. Obes Rev 2015; 16(4): 327-340.

Zuurbier LA, Kocevska D, Tiemeier H. Three authors reply. Am J Epidemiol 2015; 182(5): 470-471

Zuurbier LA, Luik AI, Hofman A, Franco OH, Someren EJW van, Tiemeier H. Fragmentation and stability of circadian activity rhythms predict mortality. The Rotterdam Study. Am J of Epidemiol 2015; 181(1): 54-63.

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Highlights publications 2014

Aben L, Heijenbrok-Kal MM, Ponds RWHM, Busschbach JJV, Ribbers GM. Long-Lasting effects of a new Memory Self-efficacy training for stroke patients: a Randomized Controlled Trial. Neurorehabilitation and Neural Repair 2014; 28(3): 199-206.

Achterberg KG, Buitendijk GHS, Kool MJ, Goorden SMI, Post L, Slump DE, Silva AJ, Woerden GM van, Kushner SA, Elgersma Y. Temporal and region-specific requirements of αCaMKП in spatial and contextual learning. Journal of Neuroscience 2014; 34 (34):11180-11187.

Benke KS, Nivard MG, Velders FP, Walters RK, Pappa I, Scheet PA, Xiao X, Ehli EA, Palmer LJ, Whitehouse AJ, Verhulst FC, Jaddoe VW, Rivadeneira F, Groen-Blokhuis MM, Beijsterveldt CE van, Davies GE, Hudziak JJ, Lubke GH, Boomsma DI, Pennell CE, Tiemeier H, Middeldorp CM. Early Genetics and Lifecourse Epidemiology Consortium. A genome-wide association meta-analysis of preschool internalizing problems. J Am Acad Child Adolesc Psychiatry 2014; 53(6): 667-676.

Benyamin B, Pourcain BSt, Davis OS, Hansell NK, Brion M-JA, Kirkpatrick RM, Cents RAM, Franic S, Miller MB, Haworth CMA, Meaburn E, Price TS, Evans DM, Timpson N, Kemp J, McArdle W, Medland SE, Yang J, Harris SE, Liewald DC, Scheet P, Xiao X, Hudziak JJ, Geus de EJC, Wellcom Trust Case Control Consortium 2 (WTCCC2), Jaddoe VWV, Starr JM, Verhulst FC, Pennell C, Tiemeier H, Iacono WG, Palmer LJ, Montgomery GW, Martin NG, Boomsma DI, Posthuma D, GcGue M, Wright MJ, Smith GD, Deary IJ, Plomin R, Visscher PM. Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. Molecular Psychiatry 2014; 19(2): 253-258.

Bergink V, Gibney SM, Drexhage HA. Autoimmunity, inflammation and psychosis: a search for peripheral markers. Biological Psychiatry 2014; 75(4): 324-331.

Bergink V, Kushner SA. Lithium during pregnancy. Am J Psychiatry 2014; 171(7): 712-715.

Brinke B ten, Klitsie PJ, Timman R, Busschbach JJ, Lange JF, Kleinrensink GJ. Anatomy education and classroom versus laparoscopic dissection-based training: a randomized study at one medical school. Acad Med 2014; 89(5): 806-810.

Cents RA, Kok R, Tiemeier H, Lucassen N, Szekely E, Bakermans-Kranenburg MJ, Hofman A, Jaddoe VW, IJzendoorn MH van, Verhulst FC, Lambregtse-van den Berg MP. Variations in maternal 5-HTTLPR affect observed sensitive parenting. J Child Psychol Psychiatry 2014; 55 (9):1025-1032.

Coesmans M, Roder CH, Smit AE, Koekkoek SK, Zeeuw CI de, Frens MA, Geest JN van der. Cerebellar motor learning deficits in medicated and medication-free men with recent-onset schizophrenia. J Psychiatry Neurosci 2014; 39(1): E3-11.

Dierckx B, Kok R, Tulen JHM, Jaddoe VW, Hofman A, Verhulst FC, Bakermans-Kranenburg MJ, IJzendoorn MH van, Tiemeier H. A prospective study of heart rate and externalising behaviours in young children. Journal of Child Psychology and Psychiatry 2014; 55(4): 402-410.

Ellegood J, Markx S, Lerch JP, Steadman PE, Genc C, Provenzano F, Kushner SA, Henkelman RM, Karayiorgou M, Gogos JA. Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion. Mol Psychiatry 2014; 19(1): 99-107.

Ellegood J, Markx S, Lerch JP, Steadman PE, Genc C, Provenzano F, Kushner SA, Henkelman RM, Karayiorgou M, Gogos JA. A highly specific pattern of volumetric brain changes due to 22q11.2 deletions in both mice and humans. Mol Psychiatry 2014; 19(1): 6.

El Marroun H, Schmidt MN, Franken IHA, Jaddoe VWV, Hofman A, Lugt A van der, Verhulst FC, Tiemeier H, White T. Prenatal tobacco exposure and brain morphology: a prospective study in young children. Neuropsychopharmacology 2014; 39: 792-800. Aben L, Heijenbrok-Kal MH, Loon EMP van, Groet E, Ponds RWHM, Busschbach JJ van, Ribbers GM. Training memory self-efficacy in the chronic stage after stroke: a randomized controlled trial. Neurorehabilitation and Neural Repair 2013; 27(2): 110-117.

El Marroun H, White TJH, Knaap NJF van der, Homberg JR, Fernandez G, Schoemaker NK, Jaddoe VWV, Hofman A, Verhulst FC, Hudziak JJ, Stricker BHC, Tiemeier H. Prenatal exposure to selective serotonin reuptake inhibitors and social responsiveness symptoms of autism: population-based study of young children. British Journal of Psychiatry 2014; 205(2): 95-102.

Gopie JP, Kuile MM ter, Timman R, Mureau MA, Tibben A. Impact of delayed implant and DIEP flap breast reconstruction on body image and sexual satisfaction: a prospective follow-up study. Psycho-Oncology 2014; 23(1): 100-107.

Guxens M, Garcia-Esteban R, Giorgis-Allemand L, Forns J, Badaloni C, Ballester F, Beelen R, Cesaroni G, Chatzi L, de Agostini M, de Nazelle A, Eeftens M, Fernandez MF, Fernandez-Somoano A, Forastiere F, Gehring U, Ghassabian A, Heude B, Jaddoe VW, Klumper C, Kogevinas M, Kramer U, Laoorque B, Lertxundi A, Lertxuni N, Murcia M, Navel V, Nieuwenhuijsen M, Porta D, Ramos R, Roumeliotaki T, Slama R, Sorensen M, Stephanou EG, Sugiri D, Tardon A, Tiemeier H, Tiesler CM, Verhulst FC, Vrijkotte T, Wilhelm M, Brunekreef B, Pershagen G, Sunyer J. Air pollution during pregnancy and childhood cognitive and psychomotor development: six European birth cohorts. Epidemiology 2014; 25(5): 636-647.

Iskandarsyah A, Klerk C de, Suardi DR, Sardarjoen SS, Passchier J. Consulting a traditional healer and negative illness perceptions are associated with non-adherence to treatment in Indonesian women with breast cancer. Psycho-Oncology 2014; 23(10): 1118-1124.

Iskandarsyah A, Klerk C de, Suardi DR, Soemitro MP, Sadarjoen SS, Passchier J. Psychosocial and cultural reasons for delay in seeking help and nonadherence to treatment in Indonesian women with breast cancer: a qualitative study. Health Psychol 2014; 33(3): 214-221.

Ismail SY, Luchtenburg AE, Timman R, Zuidema WC, Boonstra C, Weimar W, Busschbach JJ, Massay EK. Home-based family intervention increases knowledge, communication and living donation rates: a randomized controlled trial. Am J Transplant 2014; 14(8): 1862-1869.

Jansen PW, Tharner A, Ende J van der, Wake M, Raat H, Hofman A, Verhulst FC, IJzendoorn MH van, Jaddoe VW, Tiemeier H. Feeding practices and child weight: is the association bidirectional in preschool children? Am J Clin Nutr 2014; 100(5): 1329-1336.

Jansen PW, Verlinden M, Dommisse-van Berkel A, Mieloo CL, Raat H, Hofman A, Jaddoe VW, Verhulst FC, Jansen W, Tiemeier H. Teacher and peer reports of overweight and bullying among young primary school children. Pediatrics 2014; 134(3): 473-480.

Langeslag SJE, Veen FM van der, Roder CH. Attention modulates the dorsal striatum response to love stimuli. Human Brain Mapping 2014; 35(2): 503-512.

Louwerse A, Tulen JHM, Geest JN van der , Ende J van der, Verhulst FC, Greaves-Lord K. Autonomic responses to social and nonsocial pictures in adolescents with autism spectrum disorder. Autism Research 2014; 7(1): 17-27.

Micali N, Dos-Santos-Silva I, De Stavola B, Steenweg-de Graaf J, Jaddoe V, Hofman A, Verhulst FC, Steegers EAP, Tiemeier H. Fertility treatment, twin births, and unplanned pregnancies in women with eating disorders: findings from a population-based birth cohort. BJOG 2014; 121(4): 408-416.

Milaneschi Y, Hoogendijk WJG, Lips P, Heijboer AC, Schoevers R, Hemert AM van, Beekman AT, Smit JH, Pennix BW. The association between low vitamin D and depressive disorders. Molecular Psychiatry 2014; 19(4): 444-451.

Mirza SS, Bruijn RF de, Direk N, Hofman A, Koudstaal PJ, Ikram MA, Tiemeier H. Depressive symptoms predict incident dementia during short- but not long-term follow-up period. Alzheimers Dement 2014; 10(5Suppl): S323-S329.

Mirza SS, Tiemeier H, Bruijn RFAG de, Hofman A, Franco OH, Kiefte-de Jong J, Koudstaal P, Ikram MA. Coffee consumption and incident dementia. Eur J Epidemiol 2014; 29: 735-741.

Nooten FE van, Koolman X, Busschbach JJ, Brouwer WB. Thirty down, only ten to go?! Awareness and influence of a 10-year time frame in TTO. Qual Life Res 2014; 23(2): 377-384.

Offerman MP, Pruyn JF, Boer MF de, Ledeboer QC, Busschbach JJ van, Jong RJ de, Velden LA van der. Experience of palliative care for patients with head and neck cancer through the eyes of next of kin: impact of an expert center. Head Neck 2014; 36(10): 1459-1466.

Riga D, Schmitz LJ, Harst JE van der, Mourik Y van, Hoogendijk WJ, Smit AB, Vries TJ de, Spijker S. A sustained depressive state promotes a guanfacine reversible susceptibility to alcohol seeking in rats. Neuropsychopharmacology 2014; 39(5): 1115-1124.

Rijlaarsdam J, Stevens GW, Jansen PW, Ringoot AP, Jaddoe VW, Hofman A, Ayer L, Verhulst FC, Hudziak JJ, Tiemeier H. Maternal childhood maltreatment and offspring emotional and behavioral problems: maternal and paternal mechanisms of risk transmission. Child Maltreat 2014; 19(2): 67-78.

Ruchlewska A, Mulder CL, Waal R van der, Kamperman A, Gaag M van der. Crisis plans facilitated by patient advocates are better than those drawn up by clinicians: results from an RCT. Adm Policy Ment Health 2014; 41(2): 220-227.

Schwarz E, Beveren NJ van, Ramsey J, Leweke FM, Rothermindt M, Bogerts B, Steiner J, Guest PC, Bahn S. Identification of subgroups of schizophrenia patients with changes in either immune or growth factor and hormonal pathways. Schizophr Bull 2014; 40(4): 787-795.

Szekely E, Lucassen N, Tiemeier H, Bakermans-Kranenburg MJ, IJzendoorn MH van, Kok R, Jaddoe VW, Verhulst FC, Herba CM. Maternal depressive symptoms and sensitivity are related to young children’s facial expression: the Generation R study. Dev Psychopathol 2014; 26(2): 333-345.

Veen FM van der, Molen MW van der, Sahibdin PP, Franken IH. The heart-break of social rejection versus the brain wave of social acceptance. Soc Cogn Affect Neurosci 2014; 9(9): 1346-1351.

Vogelaar L, 't Spijker A van, Timman R, Tilburg AJ van, Bac D, Vogelaar T, Kuipers EJ, Busschbach JJ van, Woude CJ van der. Fatigue management in patients with IBD: a randomised controlled trial. Gut 2014; 63(6): 911-918.

Witter MP, Canto CB, Couey JJ, Koganezawa N, O’Reilly KC. Architecture of spatial circuits in the hippocampal region. Phil Trans R Soc B 2014; 369(1635): 20120515.

Yiu AP, Mercaldo V, Yan C, Richards B, Rashid AJ, Hsiang HL, Pressey J, Mahadevan V, Tran MM, Kushner SA, Woodin MA, Frankland PW, Josselyn SA. Neurons are recruited to a memory trace based on relative neuronal excitability immediately before training. Neuron 2014; 83(3): 722-735.

Zhang S-J, Ye J, Couey JJ, Witter M, Moser EI, Moser M-B. Functional connectivity of the entorhinal – hippocampal space circuit. Phil Trans R Soc B 2014; 369(1635): 20120516.

Zwet J van der, de la Croix A, de Jonge LP, Stalmeijer RE, Scherpbier AJ, Teunissen PW. The power of questions: a discourse analysis about doctor-student interaction. Med Educ 2014;48(8):806-19.

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Highlights publications 2013

Aben L, Heijenbrok-Kal MH, Loon EMP van, Groet E, Ponds RWHM, Busschbach JJ van, Ribbers GM. Training memory self-efficacy in the chronic stage after stroke: a randomized controlled trial. Neurorehabilitation and Neural Repair 2013; 27(2): 110-117.

Basten MMGJ, Althoff RR, Tiemeier H, Jaddoe VWV, Hofman A, Hudziak JJ, Verhulst FC, Ende J van der. The dysregulation profile in young children: empirically defined classes in the Generation R Study. J Am Acad Child Adolesc Psychiatry 2013; 52(8): 841-850.

Batenburg van-Eddes T, Brion MJ, Henrichs J, Jaddoe VWV, Hofman A, Verhulst FC, Lawlor DA, Smith GD, Tiemeier H. Parental depressive and anxiety symptoms during pregnancy and attention problems in children: a cross-cohort consistency study. Journal of Child Psychology and Psychiatry 2013; 54(5): 591-600.

Bergink V, Burgerhout K, Weigelt K, Pop VJ, Wit de H, Drexhage RC, Kushner SA, Drexhage HA. Immune system dysregulation in first-onset postpartum psychosis. Biological Psychiatry 2013; 73(10): 1000-1007.

Cents RAM, Diamantopoulou S, Hudziak JJ, Jaddoe VWV, Hofman A, Verhulst FC, Lambregtse-van den Berg MP, Tiemeier H. Trajectories of maternal depressive symptoms predict child problem behaviour: The Generation R Study. Psychological Medicine 2013; 43:13-25.

Couey JJ, Witoelar A, Zhang SJ, Zheng K, Ye J, Dunn B, Czajkowski R, Moser MB, Moser EI, Roudy U, Witter MP. Recurrent inhibitory circuitry as a mechanism for grid formation. Nat Neurosci 2013; 16(3): 318-324.

Cousmans M, Roder CH, Smit AE, Koekkoek SK, Zeeuw CI de, Frens MA, Geest JN van der. Cerebellar motor learning deficits in medicated and medication-free men with recent-onset schizophrenia. J Psychiatry Neurosci 2013; 38(5): 120205.

Croix A de la, Skelton J. The simulation game: an analysis of interactions between students and simulated patients. Med Educ 2013; 47(1): 49-58.

Cross-Disorder Group of the Psychiatric Genomics Consortium (including Hoogendijk WJG). Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 2013; 381: 1371-1379.

Cross-Disorder Group of the Psychiatric Genomics Consortium (including Hoogendijk WJG). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics 2013; 45(9): 984-994.

Duivenvoorden T, Vissers MM, Verhaar JA, Busschbach JJ, Gosens T, Bloem RM, Bierma-Zeinstra SM, Reijman M. Anxiety and depressive symptoms before and after total hip and knee arthroplasty: a prospective multicentre study. Osteoarthritis Cartilage 2013; 21(12): 1834-1840.

Enajat M, Damen THC, Geenen A, Timman R, Hulst RRWJ van der, Mureau MAM. Pulmonary embolism after abdominal flap breast reconstruction: prediction and prevention. Plastic and Reconstructive Surgery 2013; 131(6): 1213-1222.

Galliano E, Potters JW, Elgersma Y, Wisden W, Kushner SA, Zeeuw CI de, Hoebeek. Synaptic transmission and plasticity at inputs to murine cerebellar Purkinje cells are largely dispensable for standard nonmotor tasks. J Neurosci 2013; 33: 12599-12618.

Ghassabian A, Herba CM, Roza SJ, Govaert P, Schenk JJ, Jaddoe VW, Hofman A, White T, Verhulst FC, Tiemeier H. Infant brain structures, executive function, and attention deficit/hyperactivity problems at preschool age. A prospective study. Journal of Child Psychology and Psychiatry 2013; 54(1): 96-104.

Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, Geus de E, Jager PL de, Diez-Roux AV, Purcell S, Hu FB, Rimm EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AM, Smith AV, Sutin AR, Uitterlinden AG, Volzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig K-H, Llewellyn DJ, Raikkonen K, Tanaka T, Duijn van CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley Jr TH, Newman AB, Tiemeier H, Murabito J. A genome-wide association study of depressive symptoms. Biological Psychiatry 2013; 73: 667-678.

Hempel IS, Buck NML, Goethals KR, Marle HJC van. Unravelling sexual associations in contact and noncontact child sex offenders using the single category – implicit association test. Sexual Abuse 2013; 25(5): 444-460.

Hofman A, Murad SD, Duijn CM van, Franco OH, Goedegebure A, Ikram MA, Klaver CCW, Nijsten TEC, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol 2013; 28:889-926.

Hol JW, Lier F van, Valk M, Klimek M, Stolker RJ, Fekkes D. Effect of major and minor surgery on plasma levels of arginine, citrulline, nitric oxide metabolites, and ornithine in humans. Ann Surg 2013; 258(6): 1072-1078.

Iskandarsyah A, Klerk C de, Suardi DR, Soemitro MP, Sadarjoen SS, Passchier J. Satisfaction with information and its association with illness perception and quality of life in Indonesian breast cancer patients. Supportive Care in Cancer 2013; 21(11): 2999-3007.

Ismail SY, Claassens L, Luchtenburg AE, Roodnat JI, Zuidema WC, Weimar W, Busschbach JJ van, Massey EK. Living donor kidney transplantation among ethnic minorities in the Netherlands: a model for breaking the hurdles. Patient Education and Counseling 2013; 90(1): 118-124.

Ismail SY, Luchtenburg AE, Kal-V Gestel JA, Zuideman WC, Weimar W, Busschbach JJV, Massay EK. Modifiable factors in access to living donor kidney transplantation among diverse populations. Transplantation 2013; 96(6): 586-590.

Klaassen RM, Heins M, Luteijn LB, Gaag M van der, Beveren NJM van, and Genetic Risk and Outcome of Psychosis (GROUP) investigators. Depressive symptoms are associated with (sub)clinical psychotic symptoms in patients with non-affective psychotic disorder, siblings and healthy controls. Psychological Medicine 2013; 43(4): 747-756.

Klerk OL de, Nolte IM, Bet PM, Bosker FJ, Snieder H, Boer JA den, Bruggeman R, Hoogendijk WJ, Penninx BW. ABCB1 gene variant in influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder. Pharmacogenomics J 2013; 13(4): 349-353.

Louwerse A, Geest JN van der, Tulen JHM, Ende J van der, Van Gool AR, Verhulst FC, Greaves-Lord K. Effects of eye gaze directions of facial images on looking behavior and autonomic responses in adolescents with autism spectrum disorders. Research in Autism Spectrum Disorders 2013; 7: 1043-1054.

Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium (including Hoogendijk WJG).

A mega-analysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry 2013; 18: 497-511.

Raaf PJ de, Klerk C de, Timman R, Busschbach JJ van, Oldenmenger WH, Rijt CCD van der. Systematic monitoring and treatment of physical symptoms to alleviate fatigue in patients with advanced cancer: a randomized controlled trial. Journal of Clinical Oncology 2013; 31: 716-723.

Roder CH, Dieleman S, Veen FM van der, Linden D. Systematic review of the influence of antipsychotics on the blood oxygenation level-dependent signal of functional magnetic resonance imaging. Curr Med Chem 2013; 20(3): 448-461.

Roman GC, Ghassabian A, Bongers-Schokking JJ, Jaddoe VW, Hofman A, Rijke YB de, Verhulst FC, Tiemeier H. Association of gestational maternal hypothyroxinemia and increased autism risk. Ann Neurol 2013; 74(5): 733-742.

Timmerman L, Zuideman WC, Erdman RA, Kranenburg LW, Timman R, Ijzermans JN, Busschbach JJ van, Weimar W, Massay EK. Psychologic functioning of unspecified anonymous living kidney donors before and after donation. Transplantation 2013; 95(11): 1369-1374.

Valk RJP van der, Kiefte-de Jong JC, Sonnenschein-van der Voort AMM, Duijts L, Hafkamp-de Groen E, Moll HA, Tiemeier H, Steegers EAP, Hofman A, Jaddoe VWV, Jongste JC de. Neonatal folate, homocysteine, vitamin B12 levels and methylenetetrahydrofolate reductase variant in childhood asthma and eczema. Allergy 2013; 68: 788-795.

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Highlights publications 2012

Beerthuizen A, Stronks D, Spijker A van ‘t, Yaksh A, Hanraets B, Klein J, Huygen JPM. Demographic and medical parameters in the development of complex regional pain syndrome type 1 (CRPS1): Prospective study on 596 patients with a fracture. Pain 2012; 153: 1187-1192.

Bergink V, Bouvy PF, Vervoort JSP, Koorengevel KM, Steegers EAP, Kushner SA. Prevention of postpartum psychosis and mania in women at high risk. American Journal of Psychiatry 2012; 169: 609-615.

Dekker N, Meijer J, Koeter M, Brink W van den, Beveren N van, and GROUP investigators. Age at onset of non-affective psychosis in relation to cannabis use, other drug use and gender. Psychological Medicine 2012; 42: 1903-1911.

Direk N, Koudstaal PJ, Hofman A, Ikram A, Hoogendijk WJ, Tiemeier H. Cerebral hemodynamics and incident depression: The Rotterdam Study. Biological Psychiatry 2012; 72: 318-323.

El Marroun H, Jaddoe VWV, Hudziak JJ, Roza SJ, Steegers EAP, Hofman A, Verhulst FC, White TJH, Stricker BH, Tiemeier H. Maternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth outcomes. Archives of General Psychiatry 2012; 69(7): 706-714.

El Marroun H, Zeegers M, Steegers EAP, Ende J van der, Schenk JJ, Hofman A, Jaddoe VWV, Verhulst FC, Tiemeier H. Post-term birth and the risk of behavioural and emotional problems in early childhood. International Journal of Epidemiology 2012; 41(3): 773-781.

Janssens KAM, Oldehinkel AJ, Verhulst FC, Hunfeld JAM, Ormel J, Rosmalen JGM. Symptom-specific associations between low cortisol responses and functional somatic symptoms: the TRAILS study. Psychoneuroendocrinology 2012; 37: 332-340.

Kivimaki M, Shipley MJ, Allan CL, Sexton CE, Jokela M, Virtanen M, Tiemeier H, Ebmeier KP, Singh-Manoux A. Vascular risk status as a predictor of later-life depressive symptoms: a cohort study. Biological Psychiatry 2012; 72: 324-330.

McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, Corre T, Davies G, Kaakinen M, Lyytikainen L-P, Kristiansson K, Havulinna AS, Gogele M, Vitrart V, Tenesa A, Aulchenko Y, Hayward C, Johansson A, Boban M, Ulivi S, Robino A, Boraska V, Igl W, Wild SH, Zgaga L, Amin N, Theodoratou E, Polasek O, Girotto G, Lopez LM, Sala C, Lahti J, Laatkainen T, Prokopenko I, Kals M, Viikari J, Yang J, Anneli P, Estrada K, Hofman A, Freimer N, Martin NG, Kahonen M, Milani L, Heliovaara M, Vartiainen E, Raikkonen K, Masciullo C, Starr JM, Hicks AA, Esposito L, Kolcic I, Farrington SM, Oostra B, Zemunik T, Campbell H, Kirin M, Pehlic M, Faletra F, Porteous D, Pistis G, Widen E, Salomaa V, Koskinen S, Fischer K, Lehtmaki T, Heath A, McCarthy MI, Rivadeneira F, Montgomery GW, Tiemeier H, Hartikainen A-L, Madden PAF, d’Adamo P, Hastie ND, Gyllensten U, Wright AF, Duijn CM van, Dunlop M, Rudan I, Gasparini P, Pramstaller PP, Deary IJ, Toniolo D, Eriksson JG, Jula A, Raitakari OT, Metspalu A, Perola M, Jarvelin M-R, Uitterlinden A, Visscher PM, Wilson JF, on behalf of the ROHgen Consortium. Evidence of inbreeding depression on human height. PloS Genetics 2012; 8(7): e1002655.

Meijer JH, Dekker N, Koeter MW, Quee PJ, Beveren NJM, Meijer CJ, Genetic Risk and Outcome of Psychosis (GROUP) Investigators. Cannabic and cognitive performance in psychosis: a cross-sectional study in patients with non-affective psychotic illness and their unaffected siblings. Psychological Medicine 2012; 42: 705-716.

Micali N, Stavola De B, dos-Santos-Silva I, Steenweg-de Graaff J, Jansen PW, Jaddoe VWV, Hofman A, Verhulst FC, Steegers EAP, Tiemeier H. Perinatal outcomes and gestational weight gain in women with eating disorders: a population-based cohort study. BJOG 2012; 119(12): 1493-1502.

Ruts L, Doorn van PA, Lombardi R, Haasdijk ED, Penza P, Tulen JHM, Hempel RJ, Meiracker van den AH, Lauria G. Unmyelinated and myelinated skin nerve damage in Guillain-Barré syndrome: correlation with pain and recovery. Pain 2012; 153: 399-409.

Schwarz E, Guest PC, Rahmoune H, Harris LW, Wang L, Leweke FM, Rothermundt M, Bogerts B, Koethe D, Kranaster L, Ohrmann P, Suslow T, McAllister G, Spain M, Barnes A, Beveren van NJM, Baron-Cohen S, Steiner J, Torrey FE, Yolken RH, Bahn S. Identification of a biological signature for schizophrenia in serum. Molecular Psychiatry 2012; 17: 494-502.

Steenweg-de Graaff J, Roza SJ, Steegers EAP, Hofman A, Verhulst FC, Jaddoe VWV, Tiemeier H. Maternal folate status in early pregnancy and child emotional and behavioural problems: the Generation R study. Am J Clin Nutr 2012; 95: 1413-1421.

Sullivan P, Psychiatric Genetics Investigators (including Hoogendijk WJG). Don’t give up on GWAS. Molecular Psychiatry 2012; 17: 2-8.

Tiemeier H, Velders FP, Szekely E, Roza SJ, Dieleman G, Jaddoe VWV, Uitterlinden AG, White TJH, Bakermans-Kranenburg MJ, Hofman A, IJzendoorn van MH, Hudziak JJ, Verhulst FC. The generation R study: a review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward. Journal of the American Academy of Child & Adolescent Psychiatry 2012; 51(11): 1119-1135.

Velder FP, Dieleman G, Cents RAM, Bakermans-Kranenburg MJ, Jaddoe VWV, Hofman A, IJzendoorn van MH, Verhulst FC, Tiemeier H. Variation in the glucocorticoid receptor gene at rs41423247 moderates the effect of prenatal maternal psychological symptoms on child cortisol reactivity and behaviour. Neuropsychopharmacology 2012; 37: 2541-2549.

Verlinden M, Tiemeier H, Hudziak JJ, Jaddoe VWV, Raat H, Guxens M, Hofman A, Verhulst FC, Jansen PW. Television viewing and externalizing problems in preschool children. The Generation R study. Arch Pediatr Adolesc Med 2012; 166(10): 919-925.

Wingbermühle E, Egger JIM, Verhoeven WMA, Burgt van der I, Kessels RPC. Affective functioning and social cognition in Noonan syndrome. Psychological Medicine 2012; 42: 419-426.

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Highlights publications 2011

Bergink V, Kushner SA, Pop V, Kuijpens H, Lambregtse-Berg MP van den, Drexhage RC, Wiersinga W, Nolen WA, Drexhage HA. Prevalence of autoimmune thyroid dysfunction in postpartum psychosis. British Journal of Psychiatry 2011; 198: 264-268.

Bergink V, Lambregtse-Berg MP van den, Koorengevel KM, Kupka R, Kushner SA. First-onset psychosis occurring in the postpartum period: a prospective study. J Clin Psychiatry 2011; 72: 1531-1547.

Birkenhäger TK, Broek WW van den. Lithium addition to a tricyclic antidepressant results in optimal efficacy. Acta Psychiatr Scand 2011; 123: 83-83.

Cents RAM, Tiemeier H, Luijk MPCM, Jaddoe VWV, Hofman A, Verhulst FC, Lambregtse-van den Berg MP. Grandparental anxiety and depression predict young children’s internalizing and externalizing problems. The generation R study. Journal of Affective Disorders 2011; 128: 95-105.

Demirkan A, Penninx BWJH, Hek K, Wray NR, Aulchenko YS, Dyck R van, Geus EJC van, Hofman A, Uitterlinden Ag, Hottenga JJ,Nolen WA, Oostra BA, Sullivan PF, Willemsen G, Zitman FG, Tiemeier H, Janssens ACJW, Boomsma Di, Duijn CM van, Middeldorp CM. Genetic risk profiles for depression and anxiety in adult and elderly cohorts. Molecular Psychiatry 2011; 16: 773-783.

Dierckx B, Tharner A, Tulen JHM, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Spot the red herring: breastfeeding, fruitpurée, and infant autonomic functioning. The Generation R Study. Pediatric Research 2011; 70: 417-422.

Drexhage RC, Hoogenboezem TA, Cohen D, Versnel MA, Nole WA, Beveren NJM van, Drexhage HA. An activated set point of T-cell and monocyte inflammatory networks in recent-onset schizophrenia patients involves both pro- and anti-inflammatory forces. International Journal of Neuropsychopharmacology 2011; 14: 746-755.

Eijk MM van, Boogaard M van den, marum RJ van, Benner P, Eikelenboom P, Honing ML, Hoven B van der, Horn J, Izaks GJ, Kalf A, Karakus A, Klijn IA, Kuiper MA, Leeuw FE de, Man T de, Mast RC van der, Osse RJ, Rooij SE de, Spronk PE, Voort PH van der, Gool WA van, Slooter A. Routine use of the confusion assessment method for the intensive care unit. Am J Repir Crit Care Med 2011; 184: 340-344.

Gilden J, Staring AB, Gaag M van der, Mulder CL. Does treatment adherence therapy reduce expense of healthcare use in patients with psychotic disorders? Cost-minimization analysis in a randomized controlled trial. Schizophr Res 2011; 133: 47-53.

Guest PC, Schwarz E, Krishnamurthy D, Harris LW, Leweke FM, Rothermundt M, Beveren NJM, Rahmoune H, Bahn S. Altered levels of circulating insulin and other neuroendocrine hormones associated with the onset of schizophrenia. Psychoneuroendocrinology 2011; 36: 1092-1096.

Knegt RJ de, Bezemer G, Van Gool AR, Drenth JP, Hansen BE, Droogleever Fortuyn HA, Weegink CJ, Hengeveld MW, Janssen HL. Randomised clinical trial: escitalopram for the prevention of psychiatric adverse events during treatment with peginterferon-alpha-2a and ribavirin for chronic hepatitis C. Aliment Pharmacol Ther 2011; 34: 1306-1317.

Kohli MA, Lucae S, Saemnann PG, Schimdt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, Duijn CM van, Holsboer F, Müller- Myhsok B, Binder EB. The neuronal transporter gene SLCA15 confers risk to major depression. Neuron 2011; 70:2 52-265.

Lieverse R, Someren EJW van, Nielen MMA, Uitdehaag BMJ, Smit JH, Hoogendijk WJG. Bright light treatment in elderly patients with nonseasonal major depressive disorder. Arch Gen Psychiatry 2011; 68: 61-70.

Luppino FS, Reedt Dordtland AKB van, Wardenaar KJ, Bouvy PF, Giltay EJ, Zitmna FG, Penninx BWJH. Symptom dimensions of depression and anxiety and the metabolic syndrome. Psychosomatic Medicine 2011; 73: 257-264.

Meeter M, Murre JMJ, Janssen SMJ, Birkenhäger TK, Broek WW van den. Retrograde amnesia after electroconvulsive therapy: a temporary effect? Journal of Affective Disorders 2011; 132: 216-222.

Mies GW, Molen MW van der, Smits M, Hengeveld MW, Veen FM van der. The anterior cingulate cortex responds differently to the validity and valence of feedback in a time-estimation task. Neuroimage 2011; 56: 2321-2328.

Mies GW, Veen FM van der, Tulen JHM, Birkenhager TK, Hengeveld MW, Molen MW van der. Drug-free patients with major depression show an increased electrophysiological response to valid and invalid feedback. Psychological Medicine 2011; 41: 2515-2525.

Mohr HM, Roder C, Zimmermann J, Hummel D, Negele A, Grabhorn R. Body image distortions in bulimia nervosa: investigating body size overestimation and body size satisfaction by fMRI. NeuroImage 2011; 56: 1822-1831.

Newson RS, Boelen PA, Hek K, Hofman A, Tiemeier H. The prevalence and characteristics of complicated grief in older adults. Journal of Affective Disorders 2011; 132: 231-238.

Oosten AW, Oldenmenger WH, Zuylen C van Schmitz PI, Bannink M, Lieverse PJ, Bromberg JE, Rijt CC van der. Higher doses of opiods in patients who need palliative sedation prior to death: cause or consequence? Eur J Cancer 2011; 47: 2341-2346.

Quee PJ, Meer L van der, Bruggeman R, Haan L de, Krabbendam L, Cahn W, Mulder NCL, Wiersma D, Aleman A. Insight in psychosis: relationship with neurocognition, social cognition and clinical symptoms depends on phase of illness. Schizophrenia Bulletin 2011; 37: 29-37.

Röder CH, Mohr H, Linden DE. Retention of identity versus expression of emotional faces differs in the recruitment of limbic areas. Neuropsychologia 2011; 49: 444-453.

Roozen HG, Kroft P van der, Marle HJ van, Franken IH. The impact of craving and impulsivity on aggression in detoxified cocaine-dependent patients. Journal of Substance Abuse Treatment 2011; 40: 414-418.

Sande R van de, Nijman HLI, Noorthoorn EO, Wierdsma AI, Hellendoorn E, Staak C van der, Mulder CL. Aggression and seclusion on acute psychiatric wards: effect of short-term risk assessment. British Journal of Psychiatry 2011; 199: 473-478.

Veen FM van der, Röder CH, Mies GW, Lugt A van der, Smits M. Remedial action and feedback processing in a time-estimation task: evidence for a role of the rostral cingulate zone in behavioral adjustments. Neuroimage 2011; 54: 447-454.

Veen FM van der, Sahibdin PP. Dissociation between Medial Frontal Negativity and Cardiac responses in the Ultimatum Game: Effects of offer size and fairness. Cognitive, Affective and Behavioral Neuroscience 2011; 11: 516-525.

Velders FP, Kuninga M, Kumari M, Dekker MJ, Uitterlinden AG, Kirschbaum C, Hek K, Hofman A, Verhulst FC, Kivimaki M, Duijn CM van, Walker BR, Tiemeier H. Genetics of cortisol secretion and depressive symptoms: A candidate gene and genome wide association approach. Psychoneurdocrinology 2011; 36:1053-1061.

Vukadin M, Birkenhäger TK, Wierdsma AI, Groenland TH, Broek WW van den. Post-dexamethasone cortisol as a predictor for the efficacy of electroconvulsive therapy in depressed inpatients. Journal of Psychiatric Research 2011; 45: 1165-1169.

Winkel R van, Beveren NJ van, Simons C, Genetic Risk and Outcome of Psychosis (GROUP) investigators. AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder. Neuropsychopharmacology 2011; 36: 2529-2537.

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Highlights publications 2010

Bergink V, Koorengevel KM. Postpartum depression with psychotic features. Am J Psychiatry 2010; 167 (4):476-477.

Birkenhäger TK, Pluijms EM, Ju MR, Mulder PG, Broek WW van den. Influence of age on the efficacy of electroconvulsive therapy in major depression: a retrospective study. Journal of Affective Disorders 2010; 126:257-261.

Cinar S, Oude Voshaar RC, Janzing JGE, Birkenhager TK, Buitelaar JK, Broek WW van den. The course of depressive symptoms in unipolar depressive disorder during electroconvulsive therapy; A latent class analysis. Journal of Affective Disorders 2010; 124:141-147.

Drexhage RC, Heul-Nieuwenhuijsen L van der, Padmos RC, Beveren NJM, Cohen D, Versnel MA, Nolen WA, Drexhage HA. Inflammatory gene expression in monocytes of patients with schizophrenia: overlap and difference with bipolar disorder. A study in naturalistically treated patients. International Journal of Neuropsychopharmacology 2010; 13:1369-1381.

Evers EAT, Sambeth A, Ramaekers JG, Riedel WJ, Veen FM van der. The effects of acute tryptophan depletion on brain activation during cognition and emotional processing in healthy volunteers. Current Pharmaceutical Design 2010; 16:1998-2011.

Guest PC, Wang L, Harris LW, Burling K, Levin Y, Ernst A, Wayland MT, Umrania Y, Herberth M, Koethe D, Beveren NJM van, Rothermundt M, McAllisar G, Leweke FM, Steiner J, Bahn S. Increased levels of circulating insulin-related peptides in first-onset schizophrenia naïve schizophrenia patients. Molecular Psychiatry 2010; 15:118-119.

Hek K, Mulder CL, Luijendijk HJ, Duijn CM, Hofman A, Uitterlinden AG, Tiemeier H. The PCLO gene and depressive disorders: replication in a population-based study. Human Molecular Genetics 2010; 19 (4):731-734.

Heijnen WTCJ, Broek WW van den, Mulder PGH, Birkenhäger TK. Prevalence of trait anxiety in a sample of depressed inpatients and its influence on response to antidepressants. Journal of Psychopharmacology 2010; 24(4): 559-563.

Heijnen WT, Birkenhäger TK, Wierdsma AI, Broek WW van den. Antidepressant pharmacotherapy failure and response to subsequent electroconvulsive therapy: a meta-analysis. Journal of Clinical Psychopharmacology 2010; 30(5): 616-619.

Henrichs J, Schenk JJ, Roza SJ, Berg MP van den, Schmidt HG, Steegers EAP, Hofman A, Jaddoe VWV, Verhulst FC, Tiemeier H. Maternal psychological distress and fetal growth trajectories: The Generation R Study. Psychological Medicine 2010; 40:633-643.

Legerstee JS, Tulen JHM, Dierckx B, Treffers PDA, Verhulst FC, Utens EMWJ. CBT for childhood anxiety disorder: differential changes in selective attention between treatment responders and non-responders. Journal of Child Psychology and Psychiatry 2010; 51 (2):162-172.

Luppino FS, Wit LM de, Bouvy PF, Stijnen T, Cuijpers P, Penninx BWJH, Zitman FG. Overweight, obesity, and depression. Arch Gen Psychiatry 2010; 67 (3):220-229.

Mohr HM, Zimmerman J, Roder C, Lenz C, Overbeck G, Grabhorn R. Separating two components of body image in anorexia nervosa using fMRI. Psychol Med 2010; 40(9):1519-1529.

Newson RS, Hek K, Luijendijk HJ, Hofman A, Witteman JCM, Tiemeier H. Atherosclerosis and incident depression in late life. Arch Gen Psychiatry 2010 67(11); 1144-1151.

Röder CH, Hoogendam JM,Veen FM van der. FMRI, Antipsychotics and Schizophrenia. Influence of Different Antipsychotics on BOLD-Signal. Current Pharmaceutical Design 2010;16 (18):2012-2025.

Roozen HG, Waart R de, Kroft P van der. Community reinforcement and family training: an effective option to engage treatment-resistant substance-abusing individuals in treatment. Addiction 2010; 105: 1729-1738.

Staring ABP, Gaag M van der, Koopmans GT, Selten JP, Beveren NJM van, Hengeveld MW, Loonen AJM, Mulder CL. Treatment adherence therapy in people with psychotic disorders: randomised controlled trail. The British Journal of Psychiatry 2010; 197:448-455.

Veen FM van der, Evers EAT, Mies GW, Vuurman EFPM, Jolles J. Acute tryptophan depletion selectively attenuates cardiac slowing in an Eriksen flanker task. Journal of Psyhopharmacology 2010; 24(10):1455-1463.

Veen FM van der. Pharmacological brain imaging in the healthy and sick brain. Current Pharmaceutical Design 2010; 16(18):1978-1978.

Verhoeven WMA, CSepán R, Marcelis CLM, Lefeber DJ, Egger JIM, Tuinier S †. Sanfilippo B in an elderly female psychiatric patient: a rare but relevant diagnosis in presenile dementia. Acta Psychiatr Scand 2010; 122:162-165.

Vermeiden M, Broek WW van den, Mulder PGH, Birkenhäger TK. Influence of gender and menopausal status on antidepressant treatment response in depressed inpatients. Journal of Psychopharmacology 2010; 24 (4):497-502.

Wijkstra J, Burger H, Broek WW van den, Birkenhäger TK, Janzing JGE, Boks MPM, Bruijn JA, Loos MLM van der, Breteler LMT, Ramaekers GMGI, Verkes RJ, Nolen WA. Treatment of unipolar psychotic depression: a randomized, double-blind study comparing imipramine, venlafaxine, and venlafaxine plus quetiapine. Acta Psychiatr Scand 2010; 121:190-200.

Wijkstra J, Burger H, Broek WW van den, Birkenhäger TK, Janzing JGE, Boks MPM, Bruijn JA, Loos MLM van der, Breteler LMT, Verkes RJ, Nolen WA. Long-term response to successful acute pharmacological treatment of psychotic depression. Journal of Affective Disorders 2010; 123:238-242.

Winkel R van, Beveren NJ van, Simons C, Genetic Risk and Outcome of Psychosis (GROUP) investigators. AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder. Neuropsychopharmacology 2011; 36: 2529-2537.

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Highlights publications 2009

Berg MP van den, Ende J van der, Crijnen AAM, Jaddoe VWV, Moll HA, Mackenbach JP, Hofman A, Hengeveld MW, Tiemeier H, Verhulst FC. Paternal depressive symptoms during pregnancy are related to excessive infant crying. Pediatrics 2009; 124: e96-e103.

Berg JF van den, Luijendijk HJ, Tulen JHM, Hofman A, Knuistingh Neven A, Tiemeier H. Sleep in depression and anxiety disorders: A population-based study of elderly persons. Journal of Clinical Psychiatry 2009; 70 (8):1105-1113.

Berg JF van den, Miedema HME, Tulen JHM, Hofman A, Knuistingh Neven A, Tiemeier H. Sex difference in subjective and actigraphic sleep measures: a population-based study of elderly persons. Sleep 2009; 32 (10):1367-1375.

Birkenhäger TK, Broek WW van den, Wijkstra J, Bruijn JA, Os E van, Boks M, Verkes RJ, Janzing JGE, Nolen WA. Treatment of unipolar psychotic depression:an open study of lithium addition in refractory psychotic depression. Journal of Clinical Psychopharmacology 2009; 29: (5):513-515.

Broek WW van den, Mulder PG, Os E van, Birkenhäger TK, Pluijms E, Bruijn JA. Efficacy of venlafaxine compated with tricyclic antidepressants in depressive disorder: a meta-analysis. J Psychopharmacology 2009; 23(6):708-713.

Dierckx B, Tulen JHM, Berg MP van den, Tharner A, Jaddoe VW, Moll HA, Hofman A, Verhulst FC, Tiemeier H. Maternal Psychopathology Influences Infant Heart Rate Variability: Generation R Study. Psychosomatic Medicine 2009; 71:313-321.

Dooren S van, Duivenvoorden HJ, Passchier J, Bannnink M, Tan MBM , Oldenmenger WH, Seynaeve C, Rijt CCD van der. The Distress Thermometer assessed in woman at risk of developing hereditary breast cancer. Psycho-Oncology 2009; 18:1080-1087.

Han JH, Kushner SA, Yiu AP, Hsiang HL, Waisman A, Bontempi B, Neve RL, Frankland PW, Josselyn SA. Selective erasure of a fear memory. Science 2009; 323: 1492-1496.

Hempel RJ, Tulen JHM, Beveren NJM van, Röder CH, Hengeveld MW. Cardiovascular variability during treatment with haloperidol, olanzapine or risperidone in recent-onset schizophrenia. Journal of Psychopharmacology 2009; 23 (6):697-707.

Hol JW, Klimek M, Heide-Mulder M van der, Stronks D, Vincent AJ, Klein J, Zijlstra FJ, Fekkes D. Awake craniotomy induces fewer changes in the plasma amino acid profile than craniotomy under general anesthesia. J Neurosurg Anesthesiol 2009; 21(2):98-107.

Legerstee JS, Tulen JHM, Kallen VL, Dieleman GC, Treffers PDA, Verhulst FC, Utens EMWJ. Threat-related selective attention predicts treatment success in childhood anxiety disorders. J Am Acad Child Adolesc Psychiatry 2009; 48(2):196-205.

Lommen MJJ, Sanders AJML, Buck N, Arntz A. Psychosocial predictors of chronic Post-Traumatic stress disorder in Sri Lankan tsunami survivors. Behaviour Research and Therapy 2009; 47:60-65.

Roozen HG. Legitimizing ‘the medical prescription of money’. Addiction 2009; 104:1539-1540.

Staring ABP, Mulder CL, Duivenvoorden HJ, Haan L de, Gaag M van der. Fewer symptoms vs more side-effects in schizophrenia? Opposing pathways between antipsychotic medication compliance and quality of life. Schizophrenia Research 2009; 113 (1):27-33.

Staring ABP, Gaag M van der, Berge M van den, Duivenvoorden HJ, Mulder CL. Stigma moderates the associations of insight with depressed mood, low self-esteem, and low quality of life in patients with schizophrenia spectrum disorders. Schizophrenia Research 2009; 115:636-369.

Veen JF van, Vliet IM van, Rijk RH de, Pelt J van, Mertens B, Fekkes D, Zitman FG. Tryptophan depletion affects the autonomic stress response in generalized social anxiety disorder. Psychoneuroendocrinology 2009; 34(10):1590-1594.

Veen FM. van der, Mies GW, Molen MW van der, Evers EA. Cardiac slowing and acute tryptophan depletion: a response to the letter of Hood et al. Psychopharmacology 2009; 203:835-836.

Woerden GM van, Hoebeek FE, Gao Z, Nagaraja RY, Hoogenraad CC, Kushner SA, Hansel C, Zeeuw CI, Elgersma Y. βCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nature Neuroscience 2009; 12(7):823-825.

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Highlights publications 2008

Berg JF van den, Miedema HME, Tulen JHM, Knuistingh Neven A, Hofman A, Witteman JCM, Tiemeier H. Long sleep duration is associated with serum cholesterol in the elderly: The Rotterdam Study. Psychosomatic Medicine 2008; 70: 1005-1011.

Berg MP van den, Huizink AC, Baal GCM van, Tieman W, Enden J van der, Verhulst FC. Genetic and environmental influences on self-reported and parent reported behavior problems in young adult adoptees. Genes Brain and Behavior 2008; 7: 88-95.

Birkenhäger TK, Broek WW van den, Mulder PG,Moleman P, Bruijn JA. Efficacy of Imipramine in Psychotic Versus Nonpsychotic Depression. Journal of Clinical Psychopharmacology 2008; 28 (2): 166-170.

Birkenhager TK, Broek WW van den, Moleman P, Bruijn JA. Reply to dr. Baldessarini’s comments on “Efficay of imipramine in psychotic versus nonpsychotic depression”. Journal of Clinical Psychopharmacology 2008; 28: 717.

Drexhage RC, Padmos RC, Wit H de, Versnel MA, Hooijkaas H, Lely Aj van der, Beveren N van, Rijk RH de, Cohen D. Patients with schizophrenia show raised serum levels of the pro-inflammatory chemokine CCL2: Association with the metabolic syndrome in patients? Schizophrenia Research 2008; 102: 352-355.

Heijnen TC, van den Broek WW, Birkenhager TK. Treatment failure with a tricyclic antidepressant followed by lithium addition and response to subsequent electroconvulsive therapy. Journal of Clinical Psychiatry 2008; 69: 1887-1891.

Kooiman CG, Raats ME, Spinhoven P. Alexithymia, negative feelings in the patient and pejorative feelings in the clinician. Psychother Psychosom 2008; 77:61-62.

Krab LC, Goede Bolder A de, Aarsen FK, Pluijm SMF, Bouman MJ, Geest JN van der, Lequin M, Catsman CE, Arts WFM, Kushner SA, Silva AJ, Zeeuw CI de, Moll HA, Elgersma Y. Effect of Simvastatin on Cognitive Functioning in Children With Neurofibromatosis Type1.A Randomized Controlled Trial. JAMA 2008; 300 (3): 287-294.

Luijendijk HJ, Berg JF van den, Dekker MJHJ, Tuijl HR van, Otte W, Smit F, Hofman A, Stricker BHC, Tiemeier H. Incidence and Recurrence of Late-Life Depression. Arch Gen Psychiatry 2008; 65 (12): 1394-1401.

Nimwegen L van, Haan L de, Beveren NJ van, Laan W, Brink W van den, Linszen D. Obsessive-Compulsive Symptoms in a Randomised, Double-Blind Study With Olanzapine or Risperidone in Young Patients With Early Psychosis. Journal of Clinical Psychopharmacology 2008; 28 (2): 214-218.

Nimwegen LJ van, Haan L van, Beveren NJ van, Helm M van der, Brink W van den, Linszen D. Effect of olanzapine and risperidone on subjective wellbeing and craving for cannabis in patients with schizophrenia or related disorders: a double- blind randomized controlled trial. Can J Psychiatry 2008; 53 (6): 400-405.

Vanheusden K, Lenthe FJ van, Mulder CL, Ende J van der, Mheen D van de, Mackenbach JP, Verhulst FC. Patterns of association between alcohol consumption and internalizing and externalizing problems in young adults. Journal of the Study on Alcohol and Drugs 2008; 69 (1): 49-57.

Veen FM van der, Mies GW, Molen MW van der, Evers EA. Acute tryptophan depletion in healthy males attenuates phasic cardiac slowing but does not affect electro-cortical response to negative feedback. Psychopharmacology 2008; 199: 255-263.

Verhoeven WMA, Tuinier S. Clinical perspectives on the genetics of schizophrenia: a bottom-up orientation. Neurotox Res 2008; 14 (2-3): 141-150.

Wierdsma AI, Sytema S, Os JJ van, Mulder CL. Case registers in psychiatry: do they still have a role for research and service monitoring? Current Opinion in Psychiatry 2008; 21: 379-384.

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