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Overall research description

The Department of Psychiatry of the Erasmus MC is dedicated to excellence in clinical care, research and education.

ResearchBrain disorders constitute the largest burden of disease in all fields of medicine, both within Europe and worldwide (Wittchen HU, 2011) Yet, compared to other fields of medicine, our understanding of the underlying etiology and pathophysiology remains limited owing to the complexity of the brain and the multifactorial nature of emotions and cognition. Furthermore, the stigma of mental illness remains a profoundly significant barrier to early-intervention and treatment continuity, thereby perpetuating the consequences of psychiatric illness for patients, families, healthcare providers, and society.

Therefore, to address these complementary and interconnected aspects of mental illness, our department has undertaken specific areas of intense research focus within our research program, from ′bench to bedside to society′:


   Translational neurobiology using state-of-the-art genetic, molecular, and cellular technologies to investigate the diagnosis, treatment, and prevention of severe mental illness, including depression, mania, autism, and psychosis

   Perinatal mental health, including the iBerry cohort for diagnostic predictors and early-intervention treatments, OPPER study for postpartum psychosis, DAPPER study for pregnancy-related mental illness, and the National Center for Psychiatry and Pregnancy (LKPZ)

   Applied social and forensic psychiatry, in coordination with regional mental health care centers to address clinically-relevant questions in the field of public mental health

   Medical psychology program to investigate the emotional response to disease and treatment, in order to improve patient-centered counselling and guidance